JNTUH B.Pharm 2nd Year 1 sem Pharmacy (2-1) (R13204) Physical Pharmacy – I Engineering R13.

JNTUH B.Pharm 2nd year (R13204) Physical Pharmacy – I gives you detail (R13204) Physical Pharmacy – I Engineering R13 year subject. It will be help full you to understand you complete curriculum of the year. Objective The student shall know important physical properties of drug molecules, phase value & its importance. Different law of thermodynamics, electrolyte and non-electrolyte solutions, importance of pH and drug research. UNIT I

• Physical properties of Drug Molecules: Dielectric constant induced polarization, dipole moment, refractive index and molar refraction and optical rotatory dispersion.

UNIT II

• Phase equilibria and the phase rule:- System containing single component, System containing two component, two component system containing solid and liquid phases, three component systems
• Thermodynamics: The first law of thermodynamics. The second law of thermodynamics. The third law of thermodynamics, Free energy functions and applications.

UNIT III

• Solutions of Electrolytes: Properties of solutions of electrolytes. The Arrhenius theory of electrolyte dissociation. The modern theory of strong electrolytes and other coefficients for expressing colligative properties.
• Solutions of Non electrolytes: Concentration expressions, ideal and real solutions, colligative properties, molecular weight determinations.

Outcomes Student will know about physical properties of molecules, three laws of thermodynamics, properties of electrolytes and non electrolytes, pH and buffers. They also understand the importance of these studies in the physical pharmaceutics & Formulation development. TEXT BOOKS

• Patrick J. Sinko, Martin’s Physical Pharmacy and Pharmaceutical Sciences Fifth Edition.
• C.V.S.Subramanyam, Essentials of Physical Pharmacy, Vallabh Prakashan.
• B.S Bahl, Arun Bahl and G.D Tuli, Essentials of Physical Chemistry.
• Derle D.V., Essentials of Physical Pharmacy

REFERENCES

• Pharmacopoeias, (I.P., B.P., U.S.P. and European.)
• Martindale, The Extra Pharmacopoeia; latest edition, the Royal Pharmaceutical Society.
• Lippincott Williams and Wilkins, Remington Pharmaceutical Sciences.
• Robin. J. Haiwan, Hand Book of Pharmacy & Health Care ED, The Pharma Press UK.
• Physical Pharmaceutics by Surydevara Vidhyadhara.

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