Nanotechnology for Health Care detail syllabus for Nanoelectronics (Nano), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17NT742), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.
For all other nano 7th sem syllabus for be 2017 scheme vtu you can visit Nano 7th Sem syllabus for BE 2017 Scheme VTU Subjects. For all other Professional Elective-III subjects do refer to Professional Elective-III. The detail syllabus for nanotechnology for health care is as follows.
Course Objectives:
- To learn the basic principles and importance of Nanobiotechnology health care.
- To understand and design the nanostructures, nanodevices, nano based diagnostics techniques and devices as implants, drug delivery devices etc.
Module 1:
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Module 2:
NANOTECHNOLOGY AND DRUG DELIVERY Introduction, Advantages of Nanostructured Delivery Systems: Localized and Targeted Delivery, Controlled Delivery, Enhanced Circulation Time and Bio distribution, Drug Solubility, Intracellular Drug Delivery, Ability to Cross Biological Membranes, Enhanced Surface Areas. Activation and Targeting of Nanotechnology-Based
Drug Delivery Systems (Externally and Internally): Activation and Targeting through PhysicoChemical Stimuli and Drug Targeting through Targeting Molecules. Multifunctional Nanoparticle Systems: Multivalent Strategies and Exploiting Inherent Material Properties.
Module 3:
MATERIALS AND METHODS FOR PREPARATION OF NANOCARRIER SYSTEMS Materials: Introduction, materials used in preparation of nanoparticles as drug carrier systems: polylactic-co-glycolic acid (PLGA), poly lactic acid (PLA), polysaccharides, chitosan, alginate and their pharmaceutical applications, metal nanoparticles, iron oxide nanoparticles, metallic nanoparticles: Ag, Au, and stabilizers. Methods: Polymer precipitation methods: emulsification-solvent evaporation, emulsification-solvent diffusion, salting out method, SLN: preparation methods, Hot homogenization vs Cold homogenization techniques, Encapsulation and Drug release studies.
Module 4:
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Module 5:
LIPOSOMES AS DRUG CARRIER Liposomes: Introduction, types of liposomes, materials used in liposome preparation: phospholipids and bilayer additives, Preparation of liposomes, characterization of liposomes, stability of liposomal delivery systems: chemical stability, stability testing, pharmacokinetics, Liposomes uses: fungal treatment, cancer treatment: long circulating liposomes, size and tumor delivery, Doxil (doxorubicin) carrying liposome, Liposome vaccines, immunoliposomes and gene delivery by liposomes.
Course Outcomes:
Students can learn
- Basic concepts and applications of Nanotechnology in pharmaceutics.
- The applications of Nanotechnology in drug delivery
- Materials and methods for preparation of nanocarrier systems
- Smart polymers as drug carriers
- Liposomes as drug carrier.
Graduate Attributes (as per NBA):
- Engineering Knowledge.
- Problem Analysis.
- Design / development of solutions (partly).
- Interpretation of data.
Question paper pattern:
- The question paper will have ten questions.
- Each full Question consisting of 20 marks
- There will be 2 full questions (with a maximum of four sub questions) from each module.
- Each full question will have sub questions covering all the topics under a module.
- The students will have to answer 5 full questions, selecting one full question from each module.
Text Books:
- Nanotechnology in health care edited by P.D. Gupta and N. Udupa, first edition, 2011
- Chemical Sensors and Biosensors; Brian, R Eggins; Wiley; New York, Chichester; 2002.
- Biomedical Nanostructures by Kenneth E. Gonsalves and Craig R. Halberstadt, John wiley& sons, inc., publication, 2007.
- Nanotechnology in biology and medicine Methods, Devices, and Applications by Tuan Vo-Dinh, Taylor & Francis Group, LLC, 2007.
Reference Books:
- Electrochemical Methods: Fundamentals and Applications; Allen J Bard and Larry R Faulkner; Wiley, New York, Chichester: 2nd ed.; 2001.
- Ultrathin Electrochemical Chemo- and Biosensors: Technology and Performance in Springer Series on Chemical Sensors and Biosensors; Volume Two; Ed. Vladimir M. Mirsky; Springer, Berlin; 2004
For detail syllabus of all other subjects of BE Nano, 2017 regulation do visit Nano 7th Sem syllabus for 2017 Regulation.
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