Molecular Biology and Genetic Engineering detail syllabus for Nanoelectronics (Nano), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17NT63), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.
For all other nano 6th sem syllabus for be 2017 scheme vtu you can visit Nano 6th Sem syllabus for BE 2017 Scheme VTU Subjects. The detail syllabus for molecular biology and genetic engineering is as follows.
Course Objectives:
- To develop skills of the students in understanding the basics of Molecular Biology and Genetic engineering.
- To provide basic knowledge on replication. Transcription and Translation
- To provide knowledge on methods of cloning, construction of DNA libraries and applications of rDNA technology.
Module 1:
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Module 2:
REPLICATION AND TRANSCRIPTION Replication in prokaryotes and eukaryotes – D-loop and rolling circle mode of replication, replication of linear viral DNA. Transcription- initiation, elongation, termination, features of promoters and enhancers, transcription factors, inhibitors, post-transcriptional modification – RNA splicing, ribozyme. RNA editing. 10
Module 3:
TRANSLATION Elucidation of genetic code, Process of translation in prokaryotes and eukaryotes, posttranslational modifications, Suppressor 10
mutations, Regulation of gene expression – Lac and Trp operons.
Module 4:
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Module 5:
APPLICATIONS OF RECOMBINANT DNA TECHNOLOGY Cloning in plants, transgenic and knockout animals. Recombinant cytokines and antibodies, vaccines, gene-therapy, stem cell therapy. In-vitro fertilization, embryo transfer technology. GMO detection, identification and quantification methods. 10
Course Outcomes:
After completion of this course students will be able to:
- Understand molecular genetics
- Understand replication and transcription
- Understand translation
- Understand recombinant DNA technology
- Apply the knowledge of rDNA technology
Graduate Attributes (as per NBA):
- Engineering Knowledge.
- Problem Analysis.
- Design / development of solutions (partly).
- Interpretation of data.
Question paper pattern:
- The question paper will have ten questions.
- Each full Question consisting of 20 marks
- There will be 2 full questions (with a maximum of four sub questions) from each module.
- Each full question will have sub questions covering all the topics under a module.
- The students will have to answer 5 full questions, selecting one full question from each module.
Text Books:
- Primrose SB & Twyman, “Principles Of Gene Manipulation, An Introduction To Genetic Engineering “, Blackwell Science Publications, 2006.
- Molecular Biology and Genetic Engineering, Dr. Prasad Puthiyillam, LAP-Lambert Academic Publishing, Mauritius, 2018. ISBN: 978-613-9-82325-3
- David Friefelder, Molecular Biology, Narosa Publ. House, 1999
Reference Books:
- Sandhya Mitra, Genetic Engineering Principles and Practice, Rajiv Beri for Macmillan IndiaLtd publications, 2008.
- P. K. Gupta, Elements of biotechnology, Rastogi publications, 2004.
- Gardner / Simmons / Snustad, Principles of Genetics, Eighth Edition, John Wiley, 2000.
For detail syllabus of all other subjects of BE Nano, 2017 scheme do visit Nano 6th Sem syllabus for 2017 scheme.
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