Bioinformatics detail syllabus for Medical Electronics (Med Elec), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17ML653), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.
For all other med elec 6th sem syllabus for be 2017 scheme vtu you can visit Med Elec 6th Sem syllabus for BE 2017 Scheme VTU Subjects. For all other Professional Elective-II subjects do refer to Professional Elective-II. The detail syllabus for bioinformatics is as follows.
Module 1
Introduction To Bioinformatics: Introduction, dawn of sequencing, bioinformatics, biological sequence, genome projects, importance of bioinformatics, pattern recognition & prediction, folding problem, role of chaperones, sequence analysis, homology & analogy. Information Networks: Introduction, internet, computer network, facilities used on the internet, world wide web, web browsers, HTTP, HTML, & URL, EMBnet, NCBI, Bioinformatics Programme, Servers in India, virtual tourism. Text1:(Chapter1.1,1.2,1.3,1.4,1.5,1.6,1.7,1.8,1.9,1.10,1.11.),Chapter(2.1,2.2,2.3,2.4,2.5,2.6,2.7,2.8,2. 9,2.10, 2.11.
Module 2
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Module 3
Pairwise Alignment Techniques: Introduction, database searching, alphabets and complexity, algorithms and programs, comparing two sequences-a simple case, sub-sequences, identity and similarity. The Dotplot, local and global similarity, global alignment-Needleman & Wunsch algorithm, local alignment-Smith-Waterman algorithm, dynamic programming, pairwise database searching. Text 1: ( Chapter 6.1, 6.2,6.3,6.4,6.5,6.6,6.7,6.8,6.9,6.10,6.11,6.12,6.13 to 6.13.2.
Module 4
Multiple Sequence Alignment: Introduction, goal of multiple sequence alignment &definition, consequences, computational complexity, manual methods, simultaneous methods, progressive methods, databases of multiple alignments & searching. Secondary Database Searching: Introduction to secondary database searching, why secondary databases & its contents, regular expressions, fingerprints, blocks, hidden Markov models. Text 1: ( Chapter 7.1,7.2,7.3,7.4,7.5,7.6,7.7,7.8,7.9,7.10., Chapter 8.1,8.2,8.3 to 8.3.5.
Module 5
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Course Outcomes:
After studying this course, students will be able to:
- Apply the basic principles of biology, computer science & mathematics to extract the information from large biological databases.
- Develop new algorithms and sequence analysis methods.
- Identify appropriate method for aligning sequences, visualizing and analyzing protein structures.
- Classify the secondary structure elements and modeling protein structures from sequence.
- Explain the language of structure-function relationships, information theory, gene expression and database queries.
Question paper pattern:
- The question paper will have TEN questions.
- Each full question carry 16 marks.
- There will be TWO full questions (with maximum of THREE sub questions) from each module.
- Each full question will have questions covering all the topics under a module.
- The students will have to answer FIVE full questions, selecting ONE full question from each module.
Text Books:
- Introduction to Bioinformatics – by T. K. Attwood & D.J. Parry Smith, Pearson Education Low Price Edition, 2004.
- Fundamental Concepts – of Bioinformatics by Dan E. Krane & Michael L. Raymer, Pearson Education Low Price Edition, 2004
Reference Books:
- Bioinformatics – Concepts, Skills & Applications by S.C.Rastogi, Namita Mendiratta & Parag Rastogi, CBS Publications, 2004.
- Bioinformatics – by Andreas D. Boxevanies, Wiley Inderscience, 1998.
- Bioinformatics – Sequence and Genome Analysis by David W. Mount, Cold Spring Harbor, 2001.
For detail syllabus of all other subjects of BE Med Elec, 2017 regulation do visit Med Elec 6th Sem syllabus for 2017 Regulation.
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