Bioinformatics-I detail syllabus for Biotechnology (Biotech), 2019-20 scheme is taken from AKTU official website and presented for AKTU students. The course code (RBT-503), and for exam duration, Teaching Hr/Week, Practical Hr/Week, Total Marks, internal marks, theory marks, duration, and credits do visit complete sem subjects post given below.
For all other biotech 5th sem syllabus for b.tech 2019-20 scheme aktu you can visit Biotech 5th Sem syllabus for B.Tech 2019-20 Scheme AKTU Subjects. The detail syllabus for bioinformatics-i is as follows.
Unit I
For the complete syllabus, results, class timetable and more kindly download iStudy. It’s a lightweight, easy to use, no images, no pdfs platform to make student’s life easier.
Unit II
Sequence Alignment: Pairwise sequence alignments: Dot matrix for sequence alignment, Dynamic programming for Local and Global alignment; Multiple sequence alignment: progressive method and Iterative method; Applications of pairwise and multiple sequence alignment; Tools for multiple sequence alignment: CLUSTALW and Pileup (Algorithmic concepts).
Unit III
Scoring Matrics: Basic concept of a scoring matrix, Similarity and distance matrix, Substitution matrices: Matrices for nucleic acid and proteins sequences, PAM and BLOSUM series, principles based on which these matrices are derived; Sequence-based database searches: Need of sequence based database search, BLAST and FASTA algorithms, Various versions of basic BLAST and FASTA, Advance version of BLAST: PHI-BLAST and profile-based database searches using PSIBLAST.
Unit IV
For the complete syllabus, results, class timetable and more kindly download iStudy. It’s a lightweight, easy to use, no images, no pdfs platform to make student’s life easier.
Unit V
Protein structure prediction: Secondary structure prediction (Statistical method: Chou Fasman and GOR method, Neural Network and Nearest neighbor method) and Tertiary structures prediction (Homology Modeling); Structure visualization methods (RASMOL, CHIME etc.); Protein Structure alignment and analysis. Application of bioinformatics in drug discovery and drug designing.
Text and References Books:
- D.W.Mount; Bioinformatics- Sequence and genome analysis; Cold Spring Harbour Lab press.
- B.N.Mishra; Bioinformatics: Concept and application, Pearson Education (in press)
- O’ Reilly; Developing Bioinformatics computer skills- 1st Indian edition, SPD publication.
- Anthony J.F. Griffiths et al; An introduction to genetic analysis, 1st Ed.
- Michael Starkey and Ramnath Elaswarapu; Genomics protocols, Humana press.
- Stephen Misner & Stephen Kraeetz; bioinformatics- Methods and protocols, Humana press.
- Lawrence Hunter -Artificial intelligence & Molecular Biology, free on web
- Westhead, P; instant notes in bioinformatics; viva publications.
- Hooman H Rasid; Bioinformatics basics- Application in biological science and medicine; CRC press.
For detail syllabus of all other subjects of B.Tech Biotech, 2019-20 scheme do visit Biotech 5th Sem syllabus for 2019-20 scheme.
Don’t forget to download iStudy for the latest syllabus, results, class timetable and more.