Stem Cell & Tissue Engineering detailed syllabus scheme for Biotechnology (BT), 2019 regulation has been taken from the MU official website and presented for the Bachelor of Engineering students. For Course Code, Course Title, Test 1, Test 2, Avg, End Sem Exam, Team Work, Practical, Oral, Total, and other information, do visit full semester subjects post given below.
For 7th Sem Scheme of Biotechnology (BT), 2019 Pattern, do visit BT 7th Sem Scheme, 2019 Pattern. For the Elective-3 scheme of 7th Sem 2019 regulation, refer to BT 7th Sem Elective-3 Scheme 2019 Pattern. The detail syllabus for stem cell & tissue engineering is as follows.
Stem Cell & Tissue Engineering Syllabus for Biotechnology BE 7th Sem 2019 Pattern Mumbai University
Prerequisites:
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Course Objectives:
- To understand the developmental processes in a complex living system.
- To manipulate the cells to change and perform tasks in a carefully directed fashion.
- To understand the possibilities this technology offers in a medical field
Course Outcomes:
- This course gives an overview about the application of stem cells for regenerative medicine.
- It explains advantages and disadvantages of stem cells as therapeutics.
- The students obtain knowledge in medical applications of biomaterials as well as about basic concepts regarding design and mechanical properties of selected natural and synthetic biomaterials
- The Tissue Engineering and Regenerative Medicine educate students in two new, interdisciplinary fields in the biomedical sciences that aim to replace damaged tissue in the human body and to stimulate the bodys own regenerative processes.
- International research and development of new therapies in these areas is currently booming
Module 1
Development of multicellular organisms: Universal mechanisms of animaldevelopment, Basic anatomical features, Role of proteins and regulatory DNA in development, Approaches to understand developmental processes, Cell fate, Positional value of cell, Inductive signalling, Asymmetric cell division, Positive feedback, Morphogens and their gradients, Intrinsic programming, Patterning by sequential induction 06
Module 2
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Module 3
Epidermal renewal by stem cells: The multilayered structure of epidermis, Role of stem cells and transit amplifying cells in epidermis renewal. Renewal by multipotent stem cells: Blood cell formation, Bone marrow and Hemopoietic Stem Cells, Hematopoiesis, Contact Signals From Stromal Cells. Osteogenesis: Formation of bone & cartilage from Mesenchymal Stem Cells. 05
Module 4
Applications of stem cells in regenerative medicine: Repairing Nervous system, Liver cell proliferation and repair, Cardiac repair, Diabetes treatment, GM stem cells and Gene therapy. Ethical issues associated with stem cells 05
Module 5
Tissue Engineering: Introduction to biomaterials and tissue engineering, Elements of biomaterials, Self-assembly and growth, Mechanical concepts in biomaterials, Different protein fibers: collagen, silk, keratin. Characterization of biomaterials, Methods for the determination of biocompatibility, Biological composite materials e.g. fibers, Hierarchical design bone, wound care und suture materials, vascular implants, biomimetic and bio-inspired materials, Basic techniques to manufacture scaffolds from raw biomaterials and different prerequisites for the biomaterials 10
Module 6
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Term work
Term work shall consist of minimum eight tutorials from entire syllabus which are to be given at regular intervals Batch wise. Tutorials: 20 marks Attendance: 05 marks Total: 25 Marks
Assessment
Internal
- Assessment consists of two tests which should be conducted at proper intervals.
End Semester theory examination
- Question paper will comprise of 6 questions each carrying 20 questions.
- Total 4 questions need to be solved
- Question no.1 will be compulsory based on entire syllabus wherein sub questions can be asked.
- Remaining questions will be randomly selected from all the modules
- Weightage of marks should be proportional to number of hours assigned to each module
Reference Books:
- Molecular biology of Cell: Alberts et al.2014.(Chapter 22 and 23)
- Gordana Vunjak- Novakovic, R. Ian Freshney (2006): Culture of Cells for Tissue Engineering, Wiley
- Ulrich Meyer, Thomas Meyer, Jorg Handschel, Hans Peter Wiesmann (2009): Fundamentals of Tissue Engineering and Regenerative Medicine, Springer
- Lanza RP, Langer R, Vacanti J. Principles of Tissue Engineering. Third edition. Academic Press. 2007
For detail Syllabus of all subjects of Biotechnology (BT) 7th Sem 2019 regulation, visit BT 7th Sem Subjects of 2019 Pattern.