Cancer Biology detailed syllabus scheme for Biotechnology (BT), 2018 regulation has been taken from the MU official website and presented for the Bachelor of Engineering students. For Course Code, Course Title, Test 1, Test 2, Avg, End Sem Exam, Team Work, Practical, Oral, Total, and other information, do visit full semester subjects post given below.
For 6th Sem Scheme of Biotechnology (BT), 2018 Pattern, do visit BT 6th Sem Scheme, 2018 Pattern. For the Elective-2 scheme of 6th Sem 2018 regulation, refer to BT 6th Sem Elective-2 Scheme 2018 Pattern. The detail syllabus for cancer biology is as follows.
Cancer Biology Syllabus for Biotechnology TE 6th Sem 2018 Pattern Mumbai University
Prerequisites:
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Course Objectives:
- Studying cellular and molecular mechanisms that are deregulated in cancerous cells.
- Contribution of Genetic mutation in the development of cancer
- Environmental factors influencing susceptibility of cancer
- Treatment modalities i.e traditional chemotherapies and novel targeted therapeutic approaches
- Genetic Engineering technologies to understand cancer prevention, diagnosis, and treatment
Course Outcomes:
- By the end of the course, students should be able to describe the:
- Process of tumorigenesis at the molecular and cellular level.
- Cell cycle regulatory mechanisms in normal and tumor cells
- Role of oncogenes and tumor suppressor genes and their genetic alterations in cancer formation.
- Importance of apoptosis in normal and tumor cells
- Tumorigenesis, angiogenesis, and metastasis.
Module 1
Control of Cell proliferation, Cell Cycle and Cell Death: Process of Cell cycle, tumor suppressor genes, Cell cycle control and pRb tumor suppressor. Apoptosis and p53 tumor suppressor gene. Introduction to different forms of cancers. 06
Module 2
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Module 3
Oncogenes, growth factors, receptors and cancer: Identification of Oncogenes, Retroviruses and Oncogenes, detection of Oncogenes, Role of growth factors and receptors in carcinogenesis, RAS, NFkB, Wnt signaling in cancer. 08
Module 4
Tumor Invasion and Metastasis: Metastatic cascade, Basement membrane disruption, Three step theory of invasion, Proteinases and tumour cell invasion. Multi-step tumorigenesis and the evolution of cancer. 07
Module 5
Cancer treatment modalities: Different forms of therapy- Chemotherapy, Radiation Therapy, Immunotherapy, commonly used cancer diagnostic and prognostic molecular markers, Novel targeted therapeutic approaches. 06
Term work
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Assessment
Internal
- Assessment consists of two tests which should be conducted at proper intervals.
End Semester theory examination
- Question paper will comprise of 6 questions each carrying 20 questions.
- Total 4 questions need to be solved
- Question no.1 will be compulsory based on entire syllabus wherein sub questions can be asked.
- Remaining questions will be randomly selected from all the modules
- Weightage of marks should be proportional to number of hours assigned to each module
Reference Books:
- King R.J.B., Cancer Biology, Addision Wesley Longmann Ltd, U.K., 1996.
- Ruddon. R.W, Cancer Biology, Oxford University Press, Oxford, 1995, 2007.
- Robert Allan Weinberg, The Biology of Cancer, Volume 2, Garland Science, 2007.
For detail Syllabus of all subjects of Biotechnology (BT) 6th Sem 2018 regulation, visit BT 6th Sem Subjects of 2018 Pattern.