Downstream Processing in Biochemical Industries detailed syllabus scheme for Chemical Engineering (CH), 2017 onwards has been taken from the DBATU official website and presented for the Bachelor of Technology students. For Subject Code, Course Title, Lecutres, Tutorials, Practice, Credits, and other information, do visit full semester subjects post given below.
For 8th Sem Scheme of Chemical Engineering (CH), 2017 Onwards, do visit CH 8th Sem Scheme, 2017 Onwards. For the Elective-IX scheme of 8th Sem 2017 onwards, refer to CH 8th Sem Elective-IX Scheme 2017 Onwards. The detail syllabus for downstream processing in biochemical industries is as follows.
Downstream Processing in Biochemical Industries Syllabus for Chemical Engineering (CH) 4th Year 8th Sem 2017 DBATU
Course Outcomes:
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Unit I
Role Of Downstream Processing In Biotechnology, Role and importance of downstream processing in biotechnological processes. Problems and requirements of bioproduct purification. Economics of downstream processing in Biotechnology, cost-cutting strategies, characteristics of biological mixtures, process design criteria for various classes of bioproducts (high volume, low value products and low volume, high Value products)
Unit II
Physico-chemical basis of bio-separation processes. Recent development in product isolation (for ex. one step purification, reverse Micro cellular extraction on line membrane separation) Primary Separation And Recover Process, Cell disruption methods for intracellular products, removal of insoluble, biomass (and particulate debris) separation techniques, flocculation and sedimentation, centrifugation and filtration methods.
Unit III
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Unit IV
Enrichment Operations precipitation methods (with salts, organic solvents, and polymers, extractive separations, aqueous two-phase extraction, supercritical extraction), in situ product removal, integrated bioprocessing.
Unit V
Electrophoresis, Elecrtrophoresis of proteins and nucleic acids, 1D-2D Gels, Types of Electrophoretic techniques (Capillary and Pulse field), Product Resolution / Fractionation Chromatographic techniques- Paper, TLC, Adsorption, Ion exchange, Gel filtration, affinity chromatographic separation processes, GC, HPLC, FPLC, Chromato focusing electrophoretic separations.
Unit VI
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Text Books:
- Wankat PC. Rate controlled separations, Elsevier, 1990.
- Belter PA and Cussler E. Bioseparations, Wiley 1985.
Reference Books:
- Product Recovery in Bioprocess Technology, BIOTOL. Series, VCH, 1990.
- Asenjo J.M. Separation processes in Biotechnology, 1993, Marcel Dekkere Inc.
- Bioseparations by Siva Shankar PHI publications
For detail syllabus of all subjects of Chemical Engineering (CH) 8th Sem 2017 onwards, visit CH 8th Sem Subjects of 2017 Onwards.