Mumbai University Syllabus B.Pharm 2019 Pattern

Mumbai University B.Pharm 1st Sem Syllabus

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Mumbai University B.Pharm 7th Sem Syllabus

Mumbai University B.Pharm 8th Sem Syllabus

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For the detailed syllabus of all the other subjects of Bachelor of Pharmacy (B.Pharm) 8th Sem, 2019 Pattern, visit B.Pharm 8th Sem Subjects Syllabus for 2019 Pattern.

B.Pharm 8th Sem 2019 Pattern Scheme

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For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for project work is as follows.

BP814PW: Project Work Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

PROJECT WORK

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For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for pharmaceutical product development -theory is as follows.

BP813ET: Pharmaceutical Product Development -Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

UNIT I 10

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UNIT -II 10

1. An advanced study of Pharmaceutical Excipients in pharmaceutical product development with a special reference to the following categories
   1. Solvents and solubilizers
   2. Cyclodextrins and their applications
   3. Non – ionic surfactants and their applications
   4. Polyethylene glycols and sorbitols
   5. Suspending and emulsifying agents
   6. Semi solid excipients

UNIT -III 10

1. An advanced study of Pharmaceutical Excipients in pharmaceutical product development with a special reference to the following categories
   1. Tablet and capsule excipients
   2. Directly compressible vehicles
   3. Coat materials
   4. Excipients in parenteral and aerosols products
   5. Excipients for formulation of NDDS Selection and application of excipients in pharmaceutical formulations with specific industrial applications

UNIT -IV 8

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UNIT-V 7

Selection and quality control testing of packaging materials for pharmaceutical product development- regulatory considerations.

Recommended Books (Latest editions)

1. Pharmaceutical Statistics Practical and Clinical Applications by Stanford Bolton, CharlesBon; Marcel Dekker Inc.
2. Encyclopedia of Pharmaceutical Technology, edited by James swarbrick, Third Edition,Informa Healthcare publishers.
3. Pharmaceutical Dosage Forms, Tablets, Volume II, edited by Herbert A. Lieberman andLeon Lachman; Marcel Dekker, Inc.
4. The Theory and Practice of Industrial Pharmacy, Fourth Edition, edited by Roop kKhar, S P Vyas, Farhan J Ahmad, Gaurav K Jain; CBS Publishers and Distributors Pvt.Ltd. 2013.
5. Martins Physical Pharmacy and Pharmaceutical Sciences, Fifth Edition, edited by Patrick J. Sinko, BI Publications Pvt. Ltd.
6. Targeted and Controlled Drug Delivery, Novel Carrier Systems by S. P. Vyas and R. K.Khar, CBS Publishers and Distributors Pvt. Ltd, First Edition 2012.
7. Pharmaceutical Dosage Forms and Drug Delivery Systems, Loyd V. Allen Jr., Nicholas B.Popovich, Howard C. Ansel, 9th Ed. 40
8. Aultons Pharmaceutics – The Design and Manufacture of Medicines, Michael E. Aulton,3rd Ed.
9. Remington – The Science and Practice of Pharmacy, 20th Ed.
10. Pharmaceutical Dosage Forms – Tablets Vol 1 to 3, A. Liberman, Leon Lachman andJoseph B. Schwartz
11. Pharmaceutical Dosage Forms – Disperse Systems Vol 1 to 3, H.A. Liberman, Martin, M.R and Gilbert S. Banker.
12. Pharmaceutical Dosage Forms – Parenteral Medication Vol 1 & 2, Kenneth E. Avis andH.A. Libermann.
13. Advanced Review Articles related to the topics.

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for dietary supplements and nutraceuticals – theory is as follows.

BP812ET: Dietary Supplements and Nutraceuticals – Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Scope:

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Objective:

This module aims to provide an understanding of the concepts behind the theoretical applications of dietary supplements. By the end of the course, students should be able to:

1. Understand the need of supplements by the different group of people to maintain healthy life.
2. Understand the outcome of deficiencies in dietary supplements.
3. Appreciate the components in dietary supplements and the application.
4. Appreciate the regulatory and commercial aspects of dietary supplements including health claims.

UNIT I 10

1. Definitions of Functional foods, Nutraceuticals and Dietary supplements. Classification of Nutraceuticals, Health problems and diseases that can be prevented or cured by Nutraceuticals i.e. weight control, diabetes, cancer, heart disease, stress, osteoarthritis, hypertension etc.
2. Public health nutrition, maternal and child nutrition, nutrition and ageing, nutrition education in community.
3. Source, Name of marker compounds and their chemical nature, Medicinal uses and health benefitsof following used as nutraceuticals/functional foods: Spirulina, Soyabean, Ginseng, Garlic, Broccoli, Gingko, Flaxseeds.

UNIT -II 10

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UNIT -III 10

1. Introduction to free radicals: Free radicals, reactive oxygen species, production of free radicals in cells, damaging reactions of free radicals on lipids, proteins, Carbohydrates, nucleic acids.
2. Dietary fibres and complex carbohydrates as functional food ingredients.

UNIT -IV 8

1. Free radicals in Diabetes mellitus, Inflammation, Ischemic reperfusion injury, Cancer, Atherosclerosis, Free radicals in brain metabolism and pathology, kidney damage, muscle damage. Free radicals involvement in other disorders. Free radicals theory of ageing.
2. Antioxidants: Endogenous antioxidants – enzymatic and nonenzymatic antioxidant defence, Superoxide dismutase, catalase, Glutathione peroxidase, Glutathione Vitamin C, Vitamin E, a- Lipoic acid, melatonin Synthetic antioxidants: Butylated hydroxy Toluene, Butylated hydroxy Anisole.
3. Functional foods for chronic disease prevention

UNIT-V 7

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References:

1. Dietetics by Sri Lakshmi
2. Role of dietary fibres and neutraceuticals in preventing diseases by K.T Agusti and
3. P.Faizal: BSPunblication.
4. Advanced Nutritional Therapies by Cooper. K.A., (1996).
5. The Food Pharmacy by Jean Carper, Simon & Schuster, UK Ltd., (1988).
6. Prescription for Nutritional Healing by James F.Balch and Phyllis A.Balch 2 nd Edn.,
7. Avery Publishing Group, NY (1997).
8. G. Gibson and C.williams Editors 2000 Functional foods Woodhead Publ.Co.London.
9. Goldberg, I. Functional Foods. 1994. Chapman and Hall, New York.
10. Labuza, T.P. 2000 Functional Foods and Dietary Supplements: Safety, Good
11. Manufacturing Practice (GMPs) and Shelf Life Testing in Essentials of Functional
12. Foods M.K. Sachmidl and T.P. Labuza eds. Aspen Press.
13. Handbook of Nutraceuticals and Functional Foods, Third Edition (Modern Nutrition)
14. Shils, ME, Olson, JA, Shike, M. 1994 Modern Nutrition in Health and Disease.
15. Eighth edition. Lea and Febiger

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for advanced instrumentation techniques – theory is as follows.

BP811ET: Advanced Instrumentation Techniques – Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Scope:

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Objectives

Upon completion of the course the student shall be able to

1. understand the advanced instruments used and its applications in drug analysis
2. understand the chromatographic separation and analysis of drugs.
3. understand the calibration of various analytical instruments
4. know analysis of drugs using various analytical instruments

UNIT I 10

1. Nuclear Magnetic Resonance spectroscopy Principles of H-NMR and C-NMR, chemical shift, factors affecting chemical shift, coupling constant, Spin – spin coupling, relaxation, instrumentation and applications
2. Mass Spectrometry- Principles, Fragmentation, Ionization techniques-Electron impact, chemical ionization, MALDI, FAB, Analyzers-Time of flight and Quadrupole, instrumentation, applications

UNIT -II 10

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UNIT -III 10

1. Calibration and validation-as per ICH and USFDA guidelines
2. Calibration of following Instruments- Electronic balance, UV-Visible spectrophotometer, IR spectrophotometer, Fluorimeter, Flame Photometer, HPLC and GC

UNIT -IV 8

1. Radio immune assay:Importance, various components, Principle, different methods, Limitation and Applications of Radio immuno assay
2. Extraction techniques :General principle and procedure involved in the solid phase extraction and liquid-liquid extraction

UNIT-V 7

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Recommended Books (Latest Editions)

1. Instrumental Methods of Chemical Analysis by B.K Sharma
2. Organic spectroscopy by Y.R Sharma
3. Text book of Pharmaceutical Analysis by Kenneth A. Connors
4. Vogels Text book of Quantitative Chemical Analysis by A.I. Vogel
5. Practical Pharmaceutical Chemistry by A.H. Beckett and J.B. Stenlake
6. Organic Chemistry by I. L. Finar
7. Organic spectroscopy by William Kemp
8. Quantitative Analysis of Drugs by D. C. Garrett
9. Quantitative Analysis of Drugs in Pharmaceutical Formulations by P. D. Sethi
10. Spectrophotometric identification of Organic Compounds by Silverstein

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for experimental pharmacology -theory is as follows.

BP810ET: Experimental Pharmacology -Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Scope:

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Objectives

Upon completion of the course the student shall be able to,

1. Appreciate the applications of various commonly used laboratory animals.
2. Appreciate and demonstrate the various screening methods used in preclinical research
3. Appreciate and demonstrate the importance of biostatistics and research methodology
4. Design and execute a research hypothesis independently

UNIT I 8

Laboratory Animals:

• Study of CPCSEA and OECD guidelines for maintenance, breeding and conduct of experiments on laboratory animals, Common lab animals: Description and applications of different species and strains of animals. Popular transgenic and mutant animals.
• Techniques for collection of blood and common routes of drug administration in laboratory animals, Techniques of blood collection and euthanasia

UNIT -II 13

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UNIT -III 12

Preclinical screening models: for ANS activity, sympathomimetics, sympatholytics, parasympathomimetics, parasympatholytics, skeletal muscle relaxants, drugs acting on eye, local anaethetics

UNIT -IV 12

1. Preclinical screening models: for CVS activity- antihypertensives, diuretics, antiarrhythmic, antidyslepidemic, anti aggregatory, coagulants, and anticoagulants Preclinical screening models for other important drugs like antiulcer, antidiabetic, anticancer and antiasthmatics. 6
2. Research methodology and Bio-statistics Selection of research topic, review of literature, research hypothesis and study design Pre-clinical data analysis and interpretation using Students t test and One-way ANOVA. Graphical representation of data 6

Recommended Books (latest edition):

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For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for cosmetic science – theory is as follows.

BP809ET: Cosmetic Science – Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

UNIT I 10

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UNIT -II 10

1. Principles of formulation and building blocks of skin care products: Face wash, Moisturizing cream, Cold Cream, Vanishing cream their relative skin sensory, advantages and disadvantages. Application of these products in formulation of cosmecuticals. 5Principles of formulation and building blocks of Hair care products: Conditioning shampoo, Hair conditioners,antidandruff shampoo. Hair oils. Chemistry and formulation of Para-phylene diamine based hair dye. Principles of formulation and building blocks of oral care products: Toothpaste for bleeding gums, sensitive teeth. Teeth whitening, Mouthwash 5

UNIT -III 10

1. Sun protection, Classification of Sunscreens and SPF 2
2. Role of herbs in cosmetics: Skin Care: Aloe and turmeric Hair care: Henna and amla. Oral care: Neem and clove 6
3. Analytical cosmetics: BIS specification and analytical methods for shampoo, skin-cream and toothpaste 2

UNIT -IV 8

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UNIT -V 7

Oily and dry skin, causes leading to dry skin, skin moisturisation. Basic understanding of the terms Comedogenic, dermatitis. Cosmetic problems associated with Hair and scalp: Dandruff, Hair fall causes Cosmetic problems associated with skin: blemishes, wrinkles, acne, prickly heat and body odor. Antiperspirants and Deodorants- Actives and mechanism of action

References

1. Harrys Cosmeticology, Wilkinson, Moore, Seventh Edition, George Godwin.
2. Cosmetics – Formulations, Manufacturing and Quality Control, P.P. Sharma, 4th Edition, Vandana Publications Pvt. Ltd., Delhi.
3. Text book of cosmelicology by Sanju Nanda & Roop K. Khar, Tata Publishers.

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for cell and molecular biology -theory is as follows.

BP808ET: Cell and Molecular Biology -Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Scope:

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Objectives

Upon completion of the subject student shall be able to;

1. Summarize cell and molecular biology history.
2. Summarize cellular functioning and composition.
3. Describe the chemical foundations of cell biology.
4. Summarize the DNA properties of cell biology.
5. Describe protein structure and function.
6. Describe cellular membrane structure and function.
7. Describe basic molecular genetic mechanisms.
8. Summarize the Cell Cycle

UNIT I 10

1. Cell and Molecular Biology: Definitions theory and basics and Applications.
2. Cell and Molecular Biology: History and Summation.
3. Theory of the Cell? Properties of cells and cell membrane.
4. Prokaryotic versus Eukaryotic
5. Cellular Reproduction
6. Chemical Foundations – an Introduction and Reactions (Types)

UNIT -II 10

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UNIT -III 10

1. Proteins: Defined and Amino Acids
2. Protein Structure
3. Regularities in Protein Pathways
4. Cellular Processes
5. Positive Control and significance of Protein Synthesis

UNIT -IV 8

1. Science of Genetics
2. Transgenics and Genomic Analysis
3. Cell Cycle analysis
4. Mitosis and Meiosis
5. Cellular Activities and Checkpoints

UNIT -V 7

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Recommended Books (latest edition):

1. W.B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific publications, Oxford London.
2. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors, Delhi.
3. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
4. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.
5. Rose: Industrial Microbiology.
6. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
7. Cooper and Gunns: Tutorial Pharmacy, CBS Publisher and Distribution.
8. Peppler: Microbial Technology.
9. Edward: Fundamentals of Microbiology.
10. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
11. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company
12. B.R. Glickand J.J. Pasternak: Molecular Biotechnology: Principles and Applications of RecombinantDNA: ASM Press Washington D.C.
13. R. A Goldshy et. al.,: Kuby Immunology

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for computer aided drug design -theory is as follows.

BP807ET: Computer Aided Drug Design -Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Scope:

For the complete Syllabus, results, class timetable, and many other features kindly download the iStudy App
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Objectives

Upon completion of the course, the student shall be able to understand

1. Design and discovery of lead molecules
2. The role of drug design in drug discovery process
3. The concept of QSAR and docking
4. Various strategies to develop new drug like molecules.
5. The design of new drug molecules using molecular modelling software

UNIT I 10

1. Introduction to Drug Discovery and Development Stages of drug discovery and development 2
2. Lead discovery and Analog Based Drug Design Rational approaches to lead discovery based on traditional medicine, Random screening, Non-random screening, serendipitous drug discovery, lead discovery based on drug metabolism, lead discovery based on clinical observation. 4
3. Analog Based Drug Design:Bioisosterism, Classification, Bioisostericreplacement. Any three case studies 4

UNIT -II 10

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UNIT -III – Molecular Modeling and virtual screening techniques 10

1. Virtual Screening techniques: Drug likeness screening, Concept ofpharmacophore mapping and pharmacophore based Screening, 6
2. Molecular docking: Rigid docking, flexible docking, manual docking,Docking based screening. De novo drug design. 4

UNIT -IV 8

Informatics & Methods in drug design Introduction to Bioinformatics, chemoinformatics. ADME databases, chemical, biochemical and pharmaceutical databases.

UNIT -V 7

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Recommended Books (Latest Editions)

1. Robert GCK, ed., Drug Action at the Molecular Level University Prak Press Baltimore.
2. Martin YC. Quantitative Drug Design Dekker, New York.
3. Delgado JN, Remers WA eds Wilson & Gisvoldss Text Book of Organic Medicinal & Pharmaceutical Chemistry Lippincott, New York.
4. Foye WO Principles of Medicinal chemistry Lea & Febiger.
5. Koro lkovas A, Burckhalter JH. Essentials of Medicinal Chemistry Wiley Interscience.
6. Wolf ME, ed The Basis of Medicinal Chemistry, Burgers Medicinal Chemistry John Wiley & Sons, New York.
7. Patrick Graham, L., An Introduction to Medicinal Chemistry, Oxford University Press.
8. Smith HJ, Williams H, eds, Introduction to the principles of Drug Design Wright Boston.
9. Silverman R.B. The organic Chemistry of Drug Design and Drug Action Academic Press New York.

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.