Bioseperation & Downstream Processing Technology-II detailed syllabus scheme for Biotechnology (BT), 2019 regulation has been taken from the University of Mumbai official website and presented for the Bachelor of Engineering students. For Course Code, Course Title, Test 1, Test 2, Avg, End Sem Exam, Team Work, Practical, Oral, Total, and other information, do visit full semester subjects post given below.
For all other Mumbai University Biotechnology 8th Sem Syllabus 2019 Pattern, do visit BT 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for bioseperation & downstream processing technology-ii is as follows.
Bioseperation & Downstream Processing Technology-II Syllabus for Biotechnology BE 8th Sem 2019 Pattern Mumbai University
Prerequisites:
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Course Objectives:
- To cover the fundamentals, and design concepts of various downstream purification steps (unit operations) involved in a biochemical process.
Course Outcomes:
- Students will be able to describe theory, principle, design, application and possible integrations of unit operations in bioprocessing
Module 1
Adsorption and Ion Exchange: Introduction to Adsorption, Types of Adsorption, Adsorption Isotherms, Single Stage Adsorption, Multistage Cross Current Adsorption, Multistage Counter Current Adsorption, Equipments for Adsorption, Ion Exchange Equilibria, Ion Exchange Equipments Design and Construction of Chromatographic Columns for Bioseparations 10
Module 2
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Module 3
Equipments for Gas-Liquid Contacting applicable for Bioprocesses: Classification of equipments for gas-liquid contacting, Gas dispersed and liquid continuous phase-Sparged Vessels (Bubble Columns), Mechanically Agitated Vessels, Tray Towers, Spray Towers and Spray Chambers, Packed Towers Comparison of Packed Towers with Tray Towers. 06
Module 4
Crystallization: Solubility curve, Super saturation, Method of obtaining supersaturationEffectofheatonsizeandgrowthofcrystal,RateofC rystalgrowth and Delta-L law of crystal growth, Material and energy balance for crystallizers Crystallization equipmentdescription 08
Module 4
Drying: Introduction to drying, Equilibrium, Different types of moisture contents, Rate of Drying and drying curve, Batch Drying and calculation of time of drying, types of driers, Lyophilisation, Formulation Mixing and agitation: Principles of agitation, agitation equipment, Solid solid mixing equipment, Mixing effectiveness and Mixing index, Flow patterns in Agitated vessels, Impellers, Types of impellers, power consumption of impellers
Module 5
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Assessment
Internal
- Assessment consists of two tests which should be conducted at proper intervals.
End Semester theory examination
- Question paper will comprise of 6 questions each carrying 20 questions.
- Total 4 questions need to be solved
- Question no.1 will be compulsory based on entire syllabus wherein sub questions can be asked.
- Remaining questions will be randomly selected from all the modules
- Weightage of marks should be proportional to number of hours assigned to each module
Reference Books:
- Treybal R.E., Mass transfer operation, 3 Ed., McGraw Hill New York, 1980.
- McCabe W.L. and Smith J.C., Unit operation in chemical engineering, 5Ed. McGraw Hill New York 1993.
- Geankoplis C.J., Transport processed and unit operations, Prentice Hall, New Delhi 1997.
- RogerG.Harrison,PaulTodd,ScottR.Rudge,DemetriP.Petrides,Bioseparations Science and Engineering, Oxford University Press
- B. Shivshankar, Bioseparations: Priniples and Techniques, Eastern Economy Edition, PHI Learning Pvt. Ltd., Publishing House, New Delhi, 2012
- Bioseparation & bioprocessing (2nd Ed)2-Volume set, Ed SUBRAMANIAN Ganapathy, Wiley-VCH, ( 09-2007)
- P.A. Belter, E.L. Cussler and Wei-ShouHu., Bioseparations- Downstream Processing for Biotechnology, Wiley Interscience Publication, 1988.
- J.E. Bailey and D.F. Ollis, Biochemical Engineering Fundamentals, 2nd Edition, McGraw Hill, Inc., 1986.
- R. K. Scopes, Berlin, Protein Purification: Principles and Practice, Springer, 1982.
- Scopes Ak, Protein Purification, IRL Press, 1993
- Biotechnology: Bioprocessing, Rhem and Reed, Vol.3, 1993
- Separation and purification techniques in biotechnology, Fredreich Dechow, 1989
- Asenjo J.A. and J.Hong (Eds), Separation Processes in Biotechnolgy, Taylor and Francis
- T. Schepler et al, Biotreatment, Downstream Processing and Modeling (Advances in Biochemical Engineering /Biotechnology, Vol 56) by Springer Verlag
- Nooralbettu Krishna Prasad, Downstream Process Technology, PHI Learning, Pvt. Ltd., Eastern Economy Edition.
For detail syllabus of all other subjects of Biotechnology (BT) 8th Sem 2019 regulation, visit BT 8th Sem Subjects syllabus for 2019 regulation.