Cell Biology detailed syllabus scheme for Biotechnology (BT), 2017 regulation has been taken from the University of Mumbai official website and presented for the Bachelor of Engineering students. For Course Code, Course Title, Test 1, Test 2, Avg, End Sem Exam, Team Work, Practical, Oral, Total, and other information, do visit full semester subjects post given below.
For all other Mumbai University Biotechnology 3rd Sem Syllabus 2017 Pattern, do visit BT 3rd Sem 2017 Pattern Scheme. The detailed syllabus scheme for cell biology is as follows.
Cell Biology Syllabus for Biotechnology SE 3rd Sem 2017 Pattern Mumbai University
Prerequisites:
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Course Objectives:
- In this course, Students will explore the great diversity of all cellular form and function.
- Course emphasis is placed on the molecular mechanisms of cell metabolism, growth, division, and communication.
- This course is central to the cell biology and serves as the bridge between foundational courses in the cell and advanced courses in the complexity of sorting in the cell.
Course Outcomes:
- By the end of the course students should be able to grasp the fundamentals in Understanding the molecular organization of the cells, function and structure of The different organelles including transport mechanisms for processes like; Protein sorting, cell communication and flow of information and transport across the unit membrane, cell signaling.
- Students will have good knowledge of cancer, its types and etiology. Students will be able to appreciate all basic concepts which he may encounter in future courses in biotechnology engineering.
- Students will be ready for application of these concepts in the field of research in biotechnology.
Module 1
Cytology:
- Developmental history of cytology: Origin of cell, Robert Hookes Experiment, Cell theory, Millers Experiment Properties & Types of cells: Prokaryotic & Eukaryotic cell
- Structure and function of cells such as Viruses, Bacteria, Animal cells, Plant cells. 05
Module 2
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Module 3
Structural organization of cell and role of cell organelles in sorting and intracellular transport: 08
- Cell membrane: Function, Composition, Membrane proteins, Fluid Mosaic model, Electrical properties of membrane, Neurotransmission
- Nucleus: Nuclear Envelop, Nuclear Pore Complex & its role in nucleocytoplasmic exchange
- Overview of endomembrane system: secretory and endocytic pathway
- Endoplasmic Reticulum: SER & RER, Protein synthesis on membrane bound and free ribosomes, Protein Glycosylation in ER & Golgi complex, Membrane biosynthesis in the ER
- Golgi bodies: Movement of materials through the Golgi complex
- Structure & function of Cell wall, Mitochondria, Lysosomes
- Structure and function of cytoskeleton: (i. Microtubules – Structure & composition, MAPs, MTOCs, Dynamic properties of microtubules, Overview of motor proteins. (ii. Microfilaments – Structure, Assembly & disassembly. (iii. Intermediate filaments – Structure, Assembly & disassembly, Types and functions.
Module 4
Transport across cell:
- Bulk transport: Exocytosis, Phagocytosis, Endocytosis – Pinocytosis & Receptor mediated endocytosis
- Mechanism of transport of substances through membrane: (i. Active Transport – Ion pumps (ii. Passive Transport – Diffusion, Osmosis, Facilitated diffusion, Ion channels 05
Module 5
Cellular communication:
- General principles of cell communication: Types of adhesion, CAMs
- Extracellular matrix: Components – Collagen, Proteoglycans, Fibronectin, Laminin
- Interactions of cells with extracellular materials: Integrins, Focal Adhesions & Hemidesmosomes
- Interactions of cells with other cells: Selectins, IgSF, Cadherins, Adherens junction, Desmosomes
- Tight junctions
- Gap junctions and plasmodesmata 07
Module 6
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Term work
Term work shall consist of minimum eight tutorials from entire syllabus which are to be given at regular intervals Batch wise. Tutorials: 20 marks Attendance: 05 marks Total: 25 marks
Assessment
Internal:
- Assessment consists of average of two tests which should be conducted at proper interval.
End Semester theory examination
- Question paper will comprise of 6 questions, each carrying 20 marks.
- Total 4 questions need to be solved.
- Question No.1 will be compulsory and based on entire syllabus wherein sub questions can be asked.
- Remaining questions will be randomly selected from all the modules.
- Weightage of marks should be proportional to number of hours assigned to each Module.
Reference Books:
- Cell and Molecular biology: Concepts and Experiments, Gerald Karp, John Wiley and sons Inc, 6th Edition (2010)
- Molecular Cell Biology, H. Lodish et. al., W.H. Freeman & Co Ltd, 5th Edition (2003)
- Cell and Molecular Biology, DeRobertis; Lippincott Williams & Wilkins 8th Edition (2001)
- Molecular Biology of the Cell and the Hypercell with CDROM; Alberts, Bray; Garland Publishing 1st Edition (1999)
- Molecular Biology of the Cell with CDROM Alberts, Bruce; Johnson, Alexander; Lewis, Julian 4th Edition (2005).
For detail syllabus of all other subjects of Biotechnology (BT) 3rd Sem 2017 regulation, visit BT 3rd Sem Subjects syllabus for 2017 regulation.