BP807ET: Computer Aided Drug Design -Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Computer Aided Drug Design -Theory detailed Syllabus Scheme for Bachelor of Pharmacy (B.Pharm), 2019 regulation has been taken from the University of Mumbai official website and presented for the Pharmacy students. For Course Code, Subject Name, Continuous Mode, SE Marks, SE Duration, Total, Marks, Duration in Hours, Total Marks, and other information, do visit full semester subjects post given below.

For all other Mumbai University B.Pharm 8th Sem Syllabus 2019 Pattern, do visit B.Pharm 8th Sem 2019 Pattern Scheme. The detailed syllabus scheme for computer aided drug design -theory is as follows.

BP807ET: Computer Aided Drug Design -Theory Syllabus for B.Pharm 8th Sem 2019 Pattern Mumbai University

Scope:

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Objectives

Upon completion of the course, the student shall be able to understand

1. Design and discovery of lead molecules
2. The role of drug design in drug discovery process
3. The concept of QSAR and docking
4. Various strategies to develop new drug like molecules.
5. The design of new drug molecules using molecular modelling software

UNIT I 10

1. Introduction to Drug Discovery and Development Stages of drug discovery and development 2
2. Lead discovery and Analog Based Drug Design Rational approaches to lead discovery based on traditional medicine, Random screening, Non-random screening, serendipitous drug discovery, lead discovery based on drug metabolism, lead discovery based on clinical observation. 4
3. Analog Based Drug Design:Bioisosterism, Classification, Bioisostericreplacement. Any three case studies 4

UNIT -II 10

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UNIT -III – Molecular Modeling and virtual screening techniques 10

1. Virtual Screening techniques: Drug likeness screening, Concept ofpharmacophore mapping and pharmacophore based Screening, 6
2. Molecular docking: Rigid docking, flexible docking, manual docking,Docking based screening. De novo drug design. 4

UNIT -IV 8

Informatics & Methods in drug design Introduction to Bioinformatics, chemoinformatics. ADME databases, chemical, biochemical and pharmaceutical databases.

UNIT -V 7

For the complete Syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdf platform to make students’s lives easier.
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Recommended Books (Latest Editions)

1. Robert GCK, ed., Drug Action at the Molecular Level University Prak Press Baltimore.
2. Martin YC. Quantitative Drug Design Dekker, New York.
3. Delgado JN, Remers WA eds Wilson & Gisvoldss Text Book of Organic Medicinal & Pharmaceutical Chemistry Lippincott, New York.
4. Foye WO Principles of Medicinal chemistry Lea & Febiger.
5. Koro lkovas A, Burckhalter JH. Essentials of Medicinal Chemistry Wiley Interscience.
6. Wolf ME, ed The Basis of Medicinal Chemistry, Burgers Medicinal Chemistry John Wiley & Sons, New York.
7. Patrick Graham, L., An Introduction to Medicinal Chemistry, Oxford University Press.
8. Smith HJ, Williams H, eds, Introduction to the principles of Drug Design Wright Boston.
9. Silverman R.B. The organic Chemistry of Drug Design and Drug Action Academic Press New York.

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 8th Sem Subjects syllabus for 2019 regulation.