BP604T: Biopharmaceutics and Pharmacokinetics – Theory Syllabus for B.Pharm 6th Sem 2019 Pattern Mumbai University

Biopharmaceutics and Pharmacokinetics – Theory detailed Syllabus Scheme for Bachelor of Pharmacy (B.Pharm), 2019 regulation has been taken from the University of Mumbai official website and presented for the Pharmacy students. For Course Code, Subject Name, Continuous Mode, SE Marks, SE Duration, Total, Marks, Duration in Hours, Total Marks, and other information, do visit full semester subjects post given below.

For all other Mumbai University B.Pharm 6th Sem Syllabus 2019 Pattern, do visit B.Pharm 6th Sem 2019 Pattern Scheme. The detailed syllabus scheme for biopharmaceutics and pharmacokinetics – theory is as follows.

BP604T: Biopharmaceutics and Pharmacokinetics – Theory Syllabus for B.Pharm 6th Sem 2019 Pattern Mumbai University

Scope:

For the complete Syllabus, results, class timetable, and many other features kindly download the iStudy App
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Objectives

Upon completion of the course student shall be ableto:

1. Understand the basic concepts in biopharmaceutics and pharmacokinetics and their significance.
2. Use of plasma drug concentration-time data to calculate the pharmacokinetic parameters to describe the kinetics of drug absorption, distribution, metabolism, excretion, elimination.
3. To understand the concepts of bioavailability and bioequivalence of drug products and their significance.
4. Understand various pharmacokinetic parameters, their significance & applications

UNIT I – 10

1. Introduction to Biopharmaceutics 1
2. Absorption; Mechanisms of drug absorption through GIT, factors influencing drugabsorption though GIT, absorption of drug from Non per oral extra-vascular routes 5
3. Distribution of Tissue permeability of drugs, binding of drugs, apparent, volume of drug distribution, protein binding of drugs, factors affecting protein-drug binding. Kinetics of protein binding, Clinical significance of protein binding of drugs 4

UNIT II 10

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UNIT III 10

Pharmakokinetics: Definition and introduction of pharmacokinetics, compartment models, Non-compartment models, physiological models, One compartment open model.

1. Intravenous Injection (Bolus)
2. Intravenous infusion, extra vascular administrations, calculations of Ka, KE, t1/2, Vd, AUC Ka, Clt and CLr- definition methods of elimination, understanding of their significance and application.

UNIT IV 08

Multicompartment models: Two compartment open model. IV bolus kinetics of Multiple dosing, steady state drug level, calculation of loading and maintenancedose and their significance in clinical setting

UNIT V 07

For the complete Syllabus, results, class timetable, and many other features kindly download the iStudy App
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Reference Books (Latest Editions to be adopted)

1. Biopharmaceutics and Clinical Pharmacokinetics by, Milo Gibaldi.
2. Biopharmaceutics and Pharmacokinetics; By Robert F Notari
3. Applied biopharmaceutics and pharmacokinetics, Leon Shargel and Andrew B.C.YU 4th edition,Prentice-Hall Inernational edition.USA
4. Bio pharmaceutics and Pharmacokinetics-A Treatise, By D. M. Brahmankar and Sunil B.Jaiswal,Vallabh Prakashan Pitampura, Delhi
5. Pharmacokinetics: By Milo Glbaldi Donald, R. Mercel Dekker Inc.
6. Hand Book of Clinical Pharmacokinetics, By Milo Gibaldi and Laurie Prescott by ADIS Health Science Press.
7. Biopharmaceutics; By Swarbrick
8. Clinical Pharmacokinetics, Concepts and Applications: By Malcolm Rowland and
9. Thomas, N. Tozen, Lea and Febrger, Philadelphia, 1995.
10. Dissolution, Bioavailability and Bioequivalence, By Abdou H.M, Mack, Publishing Company,Pennsylvania 1989.
11. Biopharmaceutics and Clinical Pharmacokinetics-An introduction 4th edition Revised and expanded by Rebort F Notari Marcel Dekker Inn, New York and Basel, 1987.
12. Remingtons Pharmaceutical Sciences, By Mack Publishing Company, Pennsylvnia

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 6th Sem Subjects syllabus for 2019 regulation.