BP302T: Physicalpharmaceuticsi -Theory Syllabus for B.Pharm 3rd Sem 2019 Pattern Mumbai University

Physicalpharmaceuticsi -Theory detailed Syllabus Scheme for Bachelor of Pharmacy (B.Pharm), 2019 regulation has been taken from the University of Mumbai official website and presented for the Pharmacy students. For Course Code, Subject Name, Continuous Mode, SE Marks, SE Duration, Total, Marks, Duration in Hours, Total Marks, and other information, do visit full semester subjects post given below.

For all other Mumbai University B.Pharm 3rd Sem Syllabus 2019 Pattern, do visit B.Pharm 3rd Sem 2019 Pattern Scheme. The detailed syllabus scheme for physicalpharmaceuticsi -theory is as follows.

BP302T: Physicalpharmaceuticsi -Theory Syllabus for B.Pharm 3rd Sem 2019 Pattern Mumbai University

Scope:

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Objectives

Upon the completion of the course student shall be able to:

1. Understand various physicochemical properties of drug molecules in the designing the dosage forms
2. Know the principles of chemical kinetics & to use them for stability testing and determination of expiry date of formulations
3. Demonstrate use of physicochemical properties in the formulationdevelopment and evaluation of dosage forms.

UNIT I- Solubility of drugs 10

1. Solubility expressions, mechanisms of solute solvent interactions, ideal solubility parameters, solvation & association, quantitative approach to the factors influencing solubility of drugs, 3
2. Dissolution & drug release, diffusion principles in biological systems. Solubility of gas in liquids, solubility of liquids in liquids, (Binary solutions, ideal solutions) 3
3. Raoults law, real solutions, azeotropic mixtures, fractional distillation. Partially miscible liquids, Critical solution temperature and applications. Distribution law, its limitations and applications 4

UNIT II 10

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UNIT III 10

Surface and interfacial phenomenon: Liquid interface, surface & interfacial tensions, surface free energy, measurement of surface & interfacial tensions, spreading coefficient, adsorption at liquid interfaces, surface active agents, HLB Scale, solubilisation, detergency, adsorption at solid interface.

UNIT IV 08

Complexation and protein binding: Introduction, Classification of Complexation, Applications, methods of analysis, protein binding, Complexation and drug action, crystalline structures of complexes and thermodynamic treatment of stability constants.

UNIT V 07

For the complete Syllabus, results, class timetable, and many other features kindly download the iStudy App
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Reference Books (Latest Editions to be adopted)

1. Physical pharmacy by Alfred Martin
2. Experimental pharmaceutics by Eugene, Parott.
3. Tutorial pharmacy by Cooper and Gunn.
4. Stocklosam J. Pharmaceutical calculations, Lea &Febiger, Philadelphia.
5. Liberman H.A, Lachman C., Pharmaceutical Dosage forms, Tablets, Volume-1 to 3, MarcelDekkar Inc.
6. Liberman H.A, Lachman C, Pharmaceutical dosage forms. Disperse systems, volume 1, 2, 3 Marcel Dekkar Inc.
7. Physical pharmaceutics by Ramasamy C and Manavalan R.

For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 3rd Sem Subjects syllabus for 2019 regulation.