Biochemistry – Theory detailed Syllabus Scheme for Bachelor of Pharmacy (B.Pharm), 2019 regulation has been taken from the University of Mumbai official website and presented for the Pharmacy students. For Course Code, Subject Name, Continuous Mode, SE Marks, SE Duration, Total, Marks, Duration in Hours, Total Marks, and other information, do visit full semester subjects post given below.
For all other Mumbai University B.Pharm 2nd Sem Syllabus 2019 Pattern, do visit B.Pharm 2nd Sem 2019 Pattern Scheme. The detailed syllabus scheme for biochemistry – theory is as follows.
BP203T: Biochemistry – Theory Syllabus for B.Pharm 2nd Sem 2019 Pattern Mumbai University
Scope:
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Objectives
Upon completion of course student shell able to:
- Understand the catalytic role of enzymes, importance of enzyme inhibitors in design of new drugs, therapeutic and diagnostic applications of enzymes.
- Understand the metabolism of nutrient molecules in physiological and pathological conditions.
- Understand the genetic organization of mammalian genome and functions of DNA in the synthesis of RNAs and proteins.
UNIT I 8
- Biomolecules Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins
- Bioenergetics Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential.
- Energy rich compounds; classification; biological significances of ATP and cyclic AMP.
UNIT II 10
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UNIT III 10
- Lipid metabolism P-Oxidation of saturated fatty acid (Palmitic acid) Formation and utilization of ketone bodies; ketoacidosis De novo synthesis of fatty acids (Palmitic acid) Biological significance of cholesterol and conversion of cholesterol into bile acids, steroid hormone and vitamin D Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity.
- Amino acid metabolism General reactions of amino acid metabolism: Transamination, deamination & decarboxylation, urea cycle and its disorders Catabolism of phenylalanine and tyrosine and their metabolic disorders (Phenyketonuria, Albinism, alkeptonuria, tyrosinemia) Synthesis and significance of biological substances; 5-HT, melatonin, dopamine, noradrenaline, adrenaline Catabolism of heme; hyperbilirubinemia and jaundice
UNIT IV 10
Nucleic acid metabolism and genetic information transfer Biosynthesis of purine and pyrimidine nucleotides Catabolism of purine nucleotides and Hyperuricemia and Gout disease Organization of mammalian genome Structure of DNA and RNA and their functions DNA replication (semi conservative model) Transcription or RNA synthesis Genetic code, Translation or Protein synthesis and inhibitors
UNIT V 07
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Recommended Books: (Latest Editions)
- Principles of Biochemistry by Lehninger.
- Harpers Biochemistry by Robert K. Murry, Daryl K. Granner and Victor W. Rodwell.
- Biochemistry by Stryer.
- Biochemistry by D. Satyanarayan and U.Chakrapani
- Textbook of Biochemistry by Rama Rao.
- Textbook of Biochemistry by Deb.
- Outlines of Biochemistry by Conn and Stumpf
- Practical Biochemistry by R.C. Gupta and S. Bhargavan.
- Introduction of Practical Biochemistry by David T. Plummer. (3rd Edition)
- Practical Biochemistry for Medical students by Rajagopal and Ramakrishna.
- Practical Biochemistry by Harold Varley.
For detail syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 2nd Sem Subjects syllabus for 2019 regulation.