Clinical Immunology -Diagnostic Applications detailed Syllabus for Medical Laboratory Technology (ML), K scheme PDF has been taken from the MSBTE official website and presented for the diploma students. For Subject Code, Subject Name, Lectures, Tutorial, Practical/Drawing, Credits, Theory (Max & Min) Marks, Practical (Max & Min) Marks, Total Marks, and other information, do visit full semester subjects post given below.
For all other MSBTE Medical Laboratory Technology 5th Sem K Scheme Syllabus PDF, do visit MSBTE Medical Laboratory Technology 5th Sem K Scheme Syllabus PDF Subjects. The detailed Syllabus for clinical immunology -diagnostic applications is as follows.
Rationale
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Course Outcomes:
Students will be able to achieve & demonstrate the following COs on completion of course based learning
- Demonstrate basic principle of immunology
- Design model of antigen and antibody
- Apply techniques for identifying antigen antibody interactions
- Describe organs and cell of immune system
- Exemplify the adverse effect of immune system including allergy, reasons for immunization
hypersensitivity and elucidate the
Unit I
Introduction to Immunology 1.1 Definition of immunology, immunity, Classification of immunity with examples 1.2 Mechanisms of innate immunity 1.3 Acquired immunity 1.4 Measurement of immunity, local immunity, Herd immunity
Suggested Learning Pedagogie
Video Demonstrations Flipped Classroom Demonstration Role Play Collaborative learning
Unit II
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Unit III
Diagnostic immunology (Serology) 3.1 General features of antigen antibody reactions, Definitions of Affinity and avidity. 3.2 Principles, Requirements, Procedure and application of Precipitation -Immunoelectrophoresis, Counterimmunoelectrophoresis, One-dimensional single electroimmunodiffusion, VDRL 3.3 Principles, Requirements, Procedure and application of -Agglutination – Slide agglutination – Blood grouping, Rh factor determination, Tube agglutination – Widal test, Coombs test, and passive agglutination test 3.4 Principles, Requirements, Procedure and application of -Immunofluorescence – Direct and indirect, a. ELISA – Enzymes used in ELISA, Sandwich, Indirect, Competitive b. Immunochromatographic test – HbsAg, Dengue -IgG, IgM
Suggested Learning Pedagogie
Video Demonstrations Flipped Classroom Hands-on Site/Industry Visit Collaborative learning
Unit IV
Immune system- Structure and Function 4.1 Central (Primary) Lymphoid organs – Thymus, Bursa of Fabricus, Peripheral (Secondary) Lymphoid organs – Lymph nodes, Spleen, MALT 4.2 Cells of Lymphreticular system – Lymphocytes – T cells, B cells, Null cells, Phagocytic cells, Dendritic cells. 4.3 MHC – Types, Role in immune recognition 4.4 Immune response – Humoral immune response – primary and secondary responses, production of antibodies, monoclonal antibodies, Cell mediated immunity-Scope, Induction.
Suggested Learning Pedagogie
Video Demonstrations Flipped Classroom Presentations Role Play Collaborative learning
Unit V
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List of Experiments:
- Perform blood grouping*
- Perform Rh typing*
- Perform widal test*
- Perform ASO test*
- Perform CRP test*
- Perform RA test* 4
- HIV tridot test*
- Perform hCG test*
- HBsAg test*
- Perform Dengue IgG and IgM test
- Perform RPR test*
- Perform Malaria Antigen Test
- Demonstration of ELISA
- Demonstration of Immunofluorescence
- Demonstration of Electrophoresis
- Demonstration of Mantoux test
Self Learning
Micro Project
- Create an Immunity Classification Chart
- Explore Phagocytosis and Inflammation using models or charts
- Create a presentation on the physical and chemical barriers of the innate immune system
- Design an study experiment to measure an individual’s immune response
- Create a Visual Representation of Antigen Types
- Create a model or flowchart showing the hapten-carrier relationship
- Create a 3D Model or Diagram of Antibody Structure
- Create a visual or digital simulation demonstrating the steps in antigen-antibody reactions
Assignment
- Compare Natural vs. Artificial Immunity
- Case Study on Vaccines and Herd Immunity
- Write a report or create a presentation explaining how antigenic specificity is determined, including factors like antigenic determinants (epitopes) and cross-reactivity.
- Write a comparative report on epitopes and paratopes
- Role of Adjuvants in Immunology
- Comparative Study on Types of Immunoglobulins
- Affinity vs. Avidity: Comparative Study
Presentation
- Prepare presentation on the clinical uses of antibodies, such as in monoclonal antibody therapies, diagnostic tests (e.g., ELISA, western blot), and passive immunity
Laboratory Equipment
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Learning Materials
- R Ananthanarayan and CK Jayaram Paniker (Author) Reba Kanungo (Editor) Ananthanarayan and Paniker’s Text Book of Microbiology Universities Press (India) Pvt.,Ltd, Eleventh edition ISBN-13: 9789389211436
- Dr. C. P. Bavaja Textbook of Microbiology Arya Publication, 6th Edition, 2021 ISBN-13: 978-8178556406
- P Chakraborty A Text Book of Microbiology New Central Book Agency, Third Edition, ISBN-13: 978-8173818769
- K. Park Parks Text Book of Preventive and Social Medicine Banarsidas Bhanot Publishers ISBN-13: 978-9382219156
- Seamus J Martin, Dennis R. Burton, Ivan M Roitt, Peter J Delves Roitt’s Essential Immunology (Essentials) Wiley-Blackwell, 13th Edition ISBN-978-1118415771
Learning Websites
- https://www.nature.com/nri/ A leading journal providing reviews and articles on various immunology topics.
- https://www.youtube.com/c/MedCram Medical education channel with clear explanations of immunological concepts and current events.
- https://www.coursera.org/learn/immunology Online course on immunology offered by universities, including videos and readings.
- https://www.youtube.com/user/DoctorNajeeb Comprehensive medical lecture series, including detailed explanations of immunology.
- https://www.youtube.com/c/ProfessorDaveExplains Educational channel with videos that simplify complex immunology concepts.
- https://www.youtube.com/@shomusbiologyofficial Medical and immunology lectures in Hindi
- https://www.youtube.com/@TEACHINGPATHSHALA Medical and immunology lectures in Hindi
- https://www.youtube.com/@IndianMedicalLecture Medical lecture in hindi
- https://www.youtube.com/@MLTeducationpoint Medical and immunology lectures in Hindi
- https://www.khanacademy.org/science/biology/human-biology/im munology Comprehensive educational resources covering basic immunology concepts.
For detail Syllabus of all other subjects of Medical Laboratory Technology, K scheme do visit Medical Laboratory Technology 5th Sem Syllabus for K scheme.
For all Medical Laboratory Technology results, visit MSBTE Medical Laboratory Technology all semester results direct links.