5242: Bio-Informatics KL Diploma Syllabus for BM 5th Sem 2015 Revision SITTTR

Bio-Informatics detailed syllabus for Biomedical Engineering (BM) for 2015 revision curriculum has been taken from the SITTTRs official website and presented for the BM students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Biomedical Engineering 5th Sem scheme and its subjects, do visit BM 5th Sem 2015 revision scheme. The detailed syllabus of bio-informatics is as follows.

Course General Outcome

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General Outcome

On completion of the study the student will be able: MODULE I: MOLECULAR BIOLOGY AND GENOMIC DATABASES

1. To understand the basic concept of molecular biology
   1. To define cells, Chromosomes, DNA, RNA and Proteins
   2. To explain types of DNA and RNA
   3. To describe the Central dogma of molecular biology
2. To understand Genomic Databases
   1. To define Genomes and Genes
   2. To define Genetic code, Transcription, Translation and Protein synthesis.
   3. To explain Web based genomic and proteomic data bases: NCBI, Gen Bank

MODULE II: SEQUENCE ALIGNMENT

1. To understand sequence alignments
   1. To explain Dot Plot and Pair-wise sequence alignments.
   2. To explain local sequence similarity
   3. To explain global sequence similarity
   4. To define distance measures in sequence alignments.
   5. To state the concept of Smith-Waterman algorithm
2. To understand multiple sequence alignment
   1. To explain multiple sequence alignments
   2. To state the concept of sum-of-pairs measure
   3. To explain star and tree alignments in multiple sequence alignment
   4. To differentiate between PAM and BLOSUM
3. To know phylogenetic analysis
   1. To describe phylogenetic analysis

MODULE III: GENOMIC DATA PROCESSING

1. To understand Genomic data and its processing
   1. To state the concept of Informational view of Genomic data.
   2. To explain Genomic Signal Processing
   3. To describe DNA spectrograms
   4. To state the concept of Identification of protein coding regions
   5. To explain gene expression
   6. To state the concept of microarrays.
   7. To state the concept of microarray image analysis

MODULE IV: GENE STRUCTURE IN PROKARYOTES AND EUKARYOTES

1. To understand Gene structure in Prokaryotes and Eukaryotes
   1. To state the basic concepts and terminologies related to molecular structures
   2. To define basic molecular Visualization
   3. To explain RNA secondary structure prediction
   4. To define Protein folding
   5. To explain Protein folding problem
   6. To state the concept of Protein Threading
   7. To define Protein Visualization
   8. To state the concept of drug discovery
   9. To state the concept of BLAST for analyzing sequences

MODULE I MOLECULAR BIOLOGY AND GENOMIC DATABASES

For the complete syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdfs platform to make students’s lives easier.
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MODULE II: SEQUENCE ALIGNMENT

Dot plot-Pair-wise sequence alignments-local and global-Sequence similarity and distance measures -Smith-Waterman algorithm Multiple sequence alignment -Sum-of-Pairs measure -Star and tree alignments -PAM and BLOSUM -Phylogenetic analysis

MODULE III: GENOMIC DATA PROCESSING

For the complete syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdfs platform to make students’s lives easier.
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MODULE IV: GENE STRUCTURE IN PROKARYOTES AND EUKARYOTES

Gene structure in Prokaryotes and Eukaryotes – Molecular Structure Prediction – Basic concepts and terminologies related to molecular structures – Basic molecular Visualization – RNA secondary structure prediction – Protein folding problem – definition of Protein Threading – Protein Visualization – Basic concept of Drug Discovery. Case Study Software Tools – Use of Tools for basic and specialized sequence processing – BLAST

Text Books:

For the complete syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdfs platform to make students’s lives easier.
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Reference Books:

1. Introduction to Computational Molecular Biology – Setubal & Meidanis,Thomson: Brooks/Cole, International Student Edition, 2003
2. Bioinformatics:Sequence, structure and databanks – Higgins and Taylor,Oxford University Press, Indian Edition, 2003
3. Bioinformatics Computing – Bergeron, Prentice hall of India, 2003
4. Current topics in Computational Molecular Biology – Jiang, Xu and Zhang, Ane Books, New Delhi, 2004
5. Bioinformatics method and application Genomics,Protinomics & drug discovery – S.C Rastogi & Namitha Mendiratta,
6. Microarray Bioinformatics – Dov Stekel, Cambridge University Press

For detailed syllabus of all other subjects of Biomedical Engineering, 2015 revision curriculum do visit BM 5th Sem subject syllabuses for 2015 revision.

To see the syllabus of all other branches of diploma 2015 revision curriculum do visit all branches of SITTTR diploma 2015 revision.