{"id":1927,"date":"2016-08-06T15:36:40","date_gmt":"2016-08-06T15:36:40","guid":{"rendered":"http:\/\/www.inspirenignite.com\/jntuk\/?p=1927"},"modified":"2016-08-06T15:36:40","modified_gmt":"2016-08-06T15:36:40","slug":"jntuk-b-tech-medicinal-chemistry-i-for-r13-batch","status":"publish","type":"post","link":"https:\/\/www.inspirenignite.com\/jntuk\/jntuk-b-tech-medicinal-chemistry-i-for-r13-batch\/","title":{"rendered":"JNTUK B. Tech Medicinal chemistry &#8211; I for R13 Batch."},"content":{"rendered":"<p>JNTUK B.Tech Medicinal chemistry &#8211; I gives you detail information of Medicinal chemistry &#8211; I R13 syllabus It will be help full to understand you complete curriculum of the year<\/p><div class=\"a9916ad81d5189659b0bfae0b37c143c\" data-index=\"1\" style=\"float: none; margin:10px 0 10px 0; text-align:center;\">\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block; text-align:center;\"\r\n     data-ad-layout=\"in-article\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-client=\"ca-pub-1181153414625576\"\r\n     data-ad-slot=\"9648548092\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n\n<p><strong>UNIT-I<\/strong><br \/>\nHeterocyclic compounds:<br \/>\n1. Five and six membered ring systems with heteroatoms: Furan, pyrrole, thiophene, pyridine, imidazole, pyrazole, oxazole, isoxazole, thiazole and pyrimidine.<br \/>\n2. Fused ring systems with heteroatoms: Quinolines, isoquinolines, acridine, benzimidazole and phenothiazine.<\/p>\n<p><strong>LO :<\/strong> Nomenclature (numbering), one or two methods of preparation, important reactions, mechanisms and examples of drugs having the above ring systems.<\/p>\n<p><strong>UNIT-II<\/strong><br \/>\n1. Drug activity and physico-chemical properties: solubility, partition coefficient, hydrogen bonding, chelation, surface activity, bioisosterism, optical and geometrical isomerism, prodrugs and soft drugs.<br \/>\n2. Mechanism of drug action: receptor theories, enzyme stimulation and enzyme inhibition.<br \/>\n3. Drug metabolism: Phase I and Phase II reactions, factors affecting drug metabolism.<\/p>\n<p><strong>LO :<\/strong> Concepts involving receptors, drug-receptor interaction forces, mechanisms, equations, structures, advantages.<\/p>\n<p><strong>UNIT-III<\/strong><br \/>\nDrugs acting on CNS:<br \/>\n1. Hypnotics and anxiolytics: Phenobarbital, diazepam and alprazolam.<br \/>\n2. Antipsychotics: chlorpromazine and haloperidol.<br \/>\n3. Antiepileptics: phenytoin, carbamazepine, valproate sodium.<br \/>\n4. Antidepressants: imipramine, amitriptyline, Isocarboxazide, iproniazide.<br \/>\n5. General anaesthetics: ketamine, halothane and thiopental sodium.<\/p>\n<p><strong>LO<\/strong> : Definition, scope, classification, mode of action, Structure-Activity Relationship (SAR) wherever applicable, therapeutic uses and synthesis of compounds as given above under each class.<\/p>\n<p><strong>UNIT-IV<\/strong><br \/>\n1. Adrenergic drugs: Amphetamine, salbutamol, ephedrine, phenylephrine and dopamine.<br \/>\n2. Adrenergic blockers: Prazosine, tolazoline, Propranolol, atenolol<br \/>\n3. Cholinergic drugs: Carbachol, bethanichol.<br \/>\n4. Anticholinergics: propantheline, dicyclomine.<br \/>\n5. Neuromuscular blockers: succinyl choline.<\/p>\n<p><strong>LO<\/strong> : Definition, scope, classification, mode of action, Structure-Activity Relationship (SAR) wherever applicable, therapeutic uses and synthesis of compounds as given above under each class.<\/p>\n<p><strong>UNIT-V<\/strong><br \/>\n1. Analgesics and Non-steroidal anti-inflammatory agents (NSAIDs): paracetamol, aspirin, ibuprofen, indomethacin, diclofenac.<br \/>\n2. Narcotic analgesics : mepridine, methadone.<br \/>\n3. Local anaesthetics : benzocaine, procaine, lignocaine and dibucaine<\/p>\n<p><strong>LO<\/strong> : Definition, scope, classification, mode of action, Structure-Activity Relationship (SAR) wherever applicable, therapeutic uses and synthesis of compounds as given above under each class, an understanding of morphinans, its agonists and antagonists.<\/p>\n<p><strong>UNIT-VI<\/strong><br \/>\n1. Oral antihyperglycemic agents: tolbutamide, gliclazide, glipizide, glibenclamide, metformin and pioglitazone.<br \/>\n2. Thyroid drugs: methimazole, propylthiouracil.<br \/>\n3. H1-receptor antagonists: diphenhydramine, chlorpheniramine, chlorcyclizine, cetrizine.<br \/>\n4. H2-receptor antagonists: ranitidine<br \/>\n5. Proton pump inhibitors: Omeprazole, rabeprazole, lansaprazole.<\/p>\n<p><strong>LO :<\/strong> Definition, scope, classification, mode of action, Structure-Activity Relationship (SAR) wherever applicable, therapeutic uses and synthesis of compounds as given above under each class, an understanding of morphinans, its agonists and antagonists.<\/p>\n<p><strong>TEXT BOOKS<\/strong><\/p>\n<ul>\n<li>William O. Foye, Textbook of Medicinal Chemistry, Lea Febiger, Philadelphia.<\/li>\n<li>JH Block &amp; JM Beale (Eds), Wilson &amp; Giswold\u2019s Text book of organic Medicinal Chemistry and pharmaceutical chemistry, 11th Ed, Lipcott, Raven, Philadelphia, 2004.<\/li>\n<li>S. N. Pandeya, Textbook of mediacinal chemistry, SG Publ. Varanasi, 2003.<\/li>\n<li>Rama Rao Nadendla, Medicinal Chemistry.<\/li>\n<\/ul>\n<p><strong>REFERENCES<\/strong><\/p>\n<ul>\n<li>D. Abraham (Ed), Burger Medicinal chemistry ad Drug discovery, Vol. 1 &amp; 2. John Wiley &amp; Sons, New York 2003, 6th Ed.<\/li>\n<li>Lippincott Williams and Wilkins, Remington Pharmaceutical Sciences; 20th Edition.<\/li>\n<li>M. Atherden, Bentley and Driver\u2019s Textbook of Pharmaceutical Chemistry Ed: l. Oxford University Press, Delhi.<\/li>\n<li>B.N. Lads, MG.Mandel and F.I. way, Fundamentals of drug metabolism &amp; disposition, William &amp; welking co, Baltimore USA.<\/li>\n<li>C. Hansch, Comprehensive medicinal chemistry, Vol 1 \u2013 6 Elsevier pergmon press, Oxford.<\/li>\n<\/ul>\n<p>For more information about all JNTU updates please stay connected to us on FB and don\u2019t hesitate to ask any questions in the comment.<\/p>\n<div class=\"a9916ad81d5189659b0bfae0b37c143c\" data-index=\"2\" style=\"float: none; margin:10px 0 10px 0; text-align:center;\">\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block; text-align:center;\"\r\n     data-ad-layout=\"in-article\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-client=\"ca-pub-1181153414625576\"\r\n     data-ad-slot=\"8060844699\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>JNTUK B.Tech Medicinal chemistry &#8211; I gives you detail information of Medicinal chemistry &#8211; I R13 syllabus It will be help full to understand you complete curriculum of the year [&hellip;]<\/p>\n","protected":false},"author":2259,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1927","post","type-post","status-publish","format-standard","hentry","category-syllabus"],"_links":{"self":[{"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/posts\/1927","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/users\/2259"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/comments?post=1927"}],"version-history":[{"count":1,"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/posts\/1927\/revisions"}],"predecessor-version":[{"id":1928,"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/posts\/1927\/revisions\/1928"}],"wp:attachment":[{"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/media?parent=1927"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/categories?post=1927"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuk\/wp-json\/wp\/v2\/tags?post=1927"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}