JNTUK B.Tech Transport Phenomena in Bioprocess gives you detail information of Transport Phenomena in Bioprocess R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT I: MOMENTUM TRANSPORT-I
Mechanism of Momentum Transport: Newton’s Law of Viscosity, Non- Newtonian fluids, theory of viscosity of liquids, time dependent viscosity, viscosity measurement (cone-and-plate viscometer, coaxial cylinder rotary viscometer, impeller viscometer ), use of viscometers with biological reaction fluids, rheological properties of fermentation broth, factors affecting broth viscosity ( cell concentration, cell morphology, osmotic pressure, product and substrate concentration ), Velocity distribution in laminar flow and turbulent flow
LO: To understand various laws in momentum transfer, types of fluids, viscosity & measurement and factors effecting it.
LA: Assessment by ability to differentiate Newtonian and Non-Newtonian fluids.
UNIT II: MOMENTUM TRANSPORT-II
Equation of change for isothermal system ( equation of continuity, equation of motion, equation of mechanical energy ), interphase transport in isothermal systems ( friction factors for flow in tubes and in packed columns ) mixing, mixing mechanism, power requirements in ungassed Newtonian and Non Newtonian fluids, gassed fluids, interaction between cell and turbulent Eddies, operating conditions for turbulent shear damage. Macroscopic Balances- mass, momentum and mechanical energy balances.
LO: To understand isothermal system, mixing mechanisms and power requirement for Newtonian and Non-Newtonian fluids.
LA: Assessment by ability to demonstrate interphase transport in isothermal system and interactions.
UNIT III: ENERGY TRANSPORT
Thermal conductivity and the mechanisms of energy transport- measurement of thermal conductivity, Fourier’s law, steady state conduction, analogy between heat and momentum transfer. Temperature distribution with more than one independent variables- heating in a semi-infinite and finite slab, temperature distribution in turbulent flow-reference to stirred tank reactor, relationship between heat transfer, cell concentrations and stirring conditions
LO: To demonstrate the mechanisms of heat transfer in stirred tank reactor.
LA: Assessment by ability to demonstrate the effect of heat transfer on cell concentration and stirring conditions in stirred tank reactor.
UNIT IV: MASS TRANSPORT -I
Diffusivity, theory of diffusion, analogy between mass heat and momentum transfer, role of diffusion in bioprocessing, film theory, concentration distribution with more than one independent variable- unsteady diffusion, boundary layer theory, concentration distribution in turbulent flow- Corrosion equation. Definition of binary mass transfer coefficients, transfer coefficients at high mass transfer rates-boundary layer theory, penetration theory.
LO: To understand the diffusional properties and various film theory concepts.
LA: Assessment by ability to analyze and demonstrate the diffusion concepts during the transport.
UNIT V: MASS TRANSPORT II
Convective mass transfer, Liquid -solid mass transfer, liquid-liquid mass transfer, gas-liquid mass transfer
LO: To understand Mass transfer between various states.
LA: Assessment by ability to differentiate and identify the type of mass transfer in the given example.
UNIT VI: OXYGEN TRANSPORT
Oxygen uptake in cell cultures, Factors affecting cellular oxygen demand, oxygen transfer from gas bubbles to aerobic culture, oxygen transfer in fermenters, bubbles factors affecting oxygen transport- sparging, stirring, medium properties, antifoam agents, temperature, mass transfer correlations, measurements of kLa – oxygen balance method, dynamic method.
LO: To understand the requirement and effect of oxygen in the process.
LA: Assessment by ability to demonstrate and optimize the effect of oxygen and calculating the oxygen transfer coefficient.
NOTE: In all units relevant basic numerical problems should be practiced
TEXT BOOKS
- R. B. Bird, W. E. Stewart, E. N. Lightfoot, Transport Phenomena, 2ndedition, John Wiley and sons Singapore, 2006.
- P. M. Doran, Bioprocess Principles, 2nd edition, Academic Press, 2012.
- Harvey W. Blanch, Douglas S. Clark Biochemical Engineering, Marcecel, Dekker, 2007.
REFERENCE BOOK
- M. L. Shuler and F. Kargi, Bioprocess Engineering: Basic concepts, 2nd edition, Prentice Hall of India, 2003.
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