JNTUK B.Tech Physical Pharmacy – II gives you detail information of Physical Pharmacy – II R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT-I : Solubility and Distribution Phenomena : Solvent-solute interaction, solubility of gases in liquids, liquids in liquids, solids in liquids, distribution of solutes in immiscible solvents.
Introduction to phenomena of diffusion : Ficks first law and second law.
LO : To understand the solubility and distribution phenomenon and laws of diffusion.
UNIT-II : Kinetics: Rates and orders of the reaction. Influence of temperature and other factors on reaction rates. Decomposition and stabilization of medicinal agents, kinetics in the solid state and accelerated stability analysis (relevant numerical problems). 10
LO : To understand kinetic rates, order of reaction, decomposition pathways and methods of stabilization, stability testing methods, accelerated stability analysis.
UNIT-III : Interfacial Phenomena: Liquid interfaces, measurement of surface and interfacial tensions, adsorption at liquid interfaces. Surface active agents and systems of hydrophilic-lipophillic classification. Adsorption at solid interfaces. Electrical properties of interfaces. 08
LO : To understand theory of interfacial phenomenon, absorption, surfactants and theoretical properties of interfaces.
UNIT-IV : Micromeritics: Particle size and size distribution, methods for determining surface area, methods for determining particle size, pore size, particle shape and surface area, derived properties of powders.
LO : To learn micromeritic characteristics and their applications and significance.
UNIT-V : Rheology: Newtonian system, non-Newtonian system, thixotrophy, measurement and applications in formulations. Determination of viscosity and its applications.
LO : To understand rheology, types of flow, thixotrophy, its applications and viscosity.
UNIT –VI : Colloids: Introduction, types of colloidal systems, solubilization, Stability of colloids, optical properties, kinetic properties, electrical properties and Donnan Membrane equilibraium. 08
LO : To know colloids – types – properties – stability considerations.
TEXT BOOKS
- Patrick J. Sinko, Martin’s Physical Pharmacy and Pharmaceutical Sciences 5 Edition.
- CVS Subhramanyam, Physical Pharmacy, Vallabhprakashan.
- DeelipRaoDerle&Sai hanuman SagarBoddu. Essentials of Physical Pharmacy.
- B. S. Bahl, Arunbahl and G. D. Tuli. Essentials of Physical Chemistry.
REFERENCE
- Lippincott Williams and Wilkins, Remington Pharmaceutical Sciences
- M.E. Aulton, Pharmaceutics – The science of dosage form design, 2edition
- Bentley’s text book of Pharmaceutics. E. A. Rawlins.
- E. Shotton and K. Ridgaway, Physical Pharmaceutics, Oxford University Press, London.
- Pharmacopoiea (IP, BP, USP and European).
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