JNTUK B.Tech Pharmaceutical Technology -II gives you detail information of Pharmaceutical Technology -II R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT – I : Capsules
Advantage and disadvantages of capsule dosage forms, material for production of hard and soft gelatin capsules, sizes of capsules, capsule filling, soft processing problems in capsule manufacturing, importance of base absorption and minimum/gm factors in soft capsules, quality control, stability testing and storage of capsule dosage forms.
LO : To understand Capsule formulation, Types, Manufacturing and evaluation – Quality Control – Stability testing-storage.
UNIT – II : Microencapsulation
Types of microencapsulation and importance of microencapsulation in pharmacy, microcapsulation by coacervation phase separator, multi orifice centrifugal separation.Spray drying, spray congealing, polymerization complex emulsion, air suspension technique, and pan coating techniques, evaluation of microcapsules.
LO : To understand microencapsulation – Applications, Methods of Preparations. evaluation – Applications of Microcapsules.
UNIT – III : Tablets
Formulation of different types of tablets, granulation technology on large-scale by various techniques, types of tablet compression machinery and the equipments employed evaluation of tablets.
LO : To understand tablet formulations, additives- manufacturing methods-equipment-Evaluation of quality & Control.
UNIT – IV : Coating of Tablets
Types of coating, coating materials and their selection, formulation of coating solution, equipment for coating, coating processes, evaluation of coated tablets.
LO : To understand types of tablet coating – coating solutions- Equipment-Process- Evaluation of Coating tablets.
UNIT – V : Parenteral Products
a. Preformulation factors, routes of administration, water for injection, treatment apyrogenicity, non-aqueous vehicles, isotonicity and methods of its adjustment.
b. Formulation details, container and closures and selection.
c. Prefilling treatment, washing and sterilization of containers and closures, preparation of solution and suspensions, filling and closing of ampules, vials, infusion fluids, lyophilization & preparation of sterile powders, equipment for large-scale manufacture and evaluation of parenteral products.
d. Aseptic techniques, sources of contamination and method of prevention. Design of aseptic area, laminar flow benches, services and maintenance.
LO : To understand Formulations, Preformulations, additives, Manufacturing methods, containers, Packaging, evaluation of Parentrals – quality control, Types of sterile powders, aseptic processing facilities.
UNIT – VI : Packaging of Pharmaceutical products
Packaging components, types, specifications and methods of evaluation as per I.P. Factors influencing choice of containers, package testing, legal and other official requirements for containers, packing testing. Methods of packing of solid, liquid and semi-solid dosage forms, Factors influencing packing material, stability aspects of packaging.
LO : To understand Packaging components- types, specifications and evaluation methods of packaging materials and containers- legal and official requirements.
TEXT BOOKS
- L. Lachman, H.A, Lieberman and J.L. Kanig, Theory & Practice of industrial pharmacy, Lea & Febieger, Philadelphia Latest Edn.
- HC Ansel introduction to Pharmaceutical Dosage forms .
- Pharmaceutical Dosage forms Tablet by Lieberman, Lachman.
- CVS. Subramanyam, Pharmaceutical production and management, Vallabh Prakashan, New Delhi 2005.
REFERENCES
- Sagarian & MS Balsam, Cosmetics Sciences &Technology,Vol.1, 2 & 3
- Lippincott Williams and Wilkins, Remington Pharmaceutical Sciences
- E.A.Rawlkins Bentley’s Text Book of Pharmaceutics, Elbs publ
- S.H. Willing, M.M Tucherman and W.S. Hitchings IV, Good Manufacturing Practices for Pharmaceuticals: A Plan for Total Quality Control, 2nd ed, Marcel Dekker, Inc., New York 1998.
- Gilbert S. Banker and Christopher T Rhodes, Modern Pharmaceutics, IVth ed, marcel dekker, usa, 2005.
- Yiew chien, novel drug delivery systems, 2nd ed, marcel dekker 2003.
- Robert. A. Nash, Pharmaceutical Process Validation, 3rd Ed Marcel Dekker, 2003.
- Good Manufacturing Practices – Schedule M. Read With The Drugs And Cosmetic Rules 1945
- M.E. Aulton, Pharmaceuitcs- The science of Dosage form Design 2nd ed.
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