JNTUK B.Tech Medicinal Chemistry Lab gives you detail information of Medicinal Chemistry Lab R13 syllabus It will be help full to understand you complete curriculum of the year.
I. Synthesis of some medicinal compounds and their analogues.
- Barbituric acid from Diethyl Malonate.
- Phenytoin from Benzoin or Benzyl.
- Paracetamol from para- nitro phenol or para- aminophenol.
- 1,4- di hydro pyridine from ethyl aceto acetate.
- Quinazolinone from anthranilic acid via benzoxazinone.
- Sulfanilamide from acetanilide
- Isoniazid from -picoline.
- Antipyrine from ethyl aceto acetate.
- Benzocaine from para- nitro benzoic acid.
II. Qualitative estimation of some functional groups.
- Halogens (Strepheno’s method).
- Hydroxyl groups (Acetylation method)
- Methoxyl groups (Zeissel’s method)
- Carboxyl groups (Silver salt method).
REFERENCES
- A.I. Vogel, Text Book of Practical Organic Chemistry, 5th Edition.
- R.K. Bansal, Laboratory Manual of Organic Chemistry.
- F.G. Mann & B.C. Saunders, Practical Organic Chemistry, 4th Edition.
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