JNTUK B.Tech Immunology gives you detail information of Immunology R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT I: THE IMMUNE SYSTEM
Introduction, Phylogeny of the Immune system, Innate and acquire immunity. Immunogens, antigens, their chemical nature, Properties influencing immunogenicity, Haptens, adjuvants.
LO: To understand different types of immune system, chemical nature of antigens and immunogenicity.
LA: Assessment analyzing different types of immune response and immunogenicity.
UNIT II: BIOLOGY OF THE IMMUNE SYSTEM
Cells of the IS, Phagocytosis & Inflammation: Hematopoiesis and Cell Lineages T, B, Macrophages, Dendritic cells, Natural killer cells, Eosinophil’s, Neutrophils, Mast cells. Phagocytosis & Inflammation.
LO: To understand different cells of immune system.
LA: Assessment by ability to differentiate cells and demonstrating the mechanism of its action.
UNIT –III LYMPHOID ORGANS
Primary and Secondary organs of lymphoid organs- Thymus, Spleen, Lymphnode, lymphoid follicle, MALT (CALT, BALT, GALT)
LO: To understand the structure and functions of lymphoid organs.
LA: Assessment by analyzing and interpreting the action of different lymphoid cells.
UNIT IV: HUMORAL IMMUNITY
B-lymphocytes, their lineage, Immunoglobulins, their structure & function, classes, sub classes, Isotype, allotypes, Idiotypes. Hybridoma Technology Monoclonal antibodies their application. Immunotoxing chimeric antibodies and abzymes, Immunoglobulin gene organization and rearrangement. Generation of immunoglobulin diversity &class switch. B cell maturation & Activation. B cells differentiation and effector functions. Antigen-Antibody intereactions. Hypersensitivity: Types of hypersensitivity, Principle, mechanisms their relevance & significance. Complement System.
LO: To understand different types of antibodies, its diversity, its interactions with antigens and different types of hypersensitivity reactions.
LA: Assessment by ability to demonstrate different antigen-antibody interactions and hypersensitivity reactions.
UNIT V: CELL MEDIATED IMMUNITY
T-cells sub classes their lineage, MHC, Ag processing and presentation, TCR diversity, T cell ontogeny: maturation, activation and effector functions.
LO: To understand different classes of T-cell and mechanism of cell mediated immunity.
LA: Assessment by ability to demonstrate cell mediated immune response to a stimuli.
UNIT VI: TRANSPLANTATION, AUTOIMMUNITY AND TUMORS
Transplantation- Graft rejection and mechanisms prevention of graft rejection, immuno suppressive drugs, Autoimmunity – experimental models of autoimmune disease. Treatment of autoimmune disorders and Tumor immunology.
LO: To understand types and treatment to autoimmune disorders.
LA: Assessment by demonstration of drugs to various autoimmune disorders.
TEXT BOOKS
- E. Roitt Essential Immunology, 12th edition, Wiley Blackwell Scientific publications Oxford, 2011.
- Richard A Goldsby, Thomas J Kindt, Barbara A Osborne Kuby, Immunology, 6th edition, W H Freeman and Company, 2006.
- Khan. F. H The Elements Of immunology, Pearson education, 2009.
REFERENCES
- Abul Abbas and Litchman, Cellular Molecular Immunology, 7th edition, Saunders Education, 2011.
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