JNTUK B.Tech Genetics gives you detail information of Genetics R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT – I: PHYSICAL BASIS OF HEREDITY
Basic laws of inheritance, modification of Mendel’s ratios, multiple factors of inheritance. Genes and environment, identification of genetic material – classical experiments, Hershey chase, Avery McLeod etc. Packing of DNA, organization of genetic material in prokaryotes and eukaryotes.
LO: To demonstrate Mendel’s laws pictorially.
LA: Assessment of practical demonstration of Mendel’s laws.
UNIT – II: LINKAGE AND RECOMBINATION
Chromosomal inheritance, Linkage and Crossing over, Mechanism of Recombination, Methods of Transduction – Generalized, Specialized and Abortive, Bacteriophages – Lytic and Lysogenic life cycle, Molecular mechanism of Transformation, Bacterial Conjugation.
LO: To study the various concepts of inheritance and recombination.
LA: Assessment by practical observation.
UNIT-III: FACTORS ASSOCIATED WITH SEX DETERMINATION
Mechanism of sex determination in Insect (Fruit Fly), plants (Melandrium), F and HFr transfer, Mechanism of transfer. Sex determination and developments in Humans, Dosage compensation, Maryleons Hypothesis, Sex linked disorders in Human beings – Fragile-X syndrome, Down’s syndrome.
LO: To demonstrate sex determination in prokaryotes and eukaryotes and observation of genetic disorders in humans.
LA: Assessment by practical demonstration & patient’s observation.
UNIT – IV: CHROMOSOME STRUCTURE, ORGANIZATION AND ABERRATIONS
Chromosome morphology, classification, Karyotyping, Special Chromosomes, Chromosome aberrations, Origin, types and Cytogenetic effects, Gene Mapping, Test Crosses.
LO: To demonstrate the chromosome structure and its organization.
LA: Assessment by practical observation of chromosomes of different tissues.
Unit :- V: MUTATIONS AND DISEASES
Mutations, types of mutations, Snps and related diseases ( Turner’s syndrome, colour blindness,klinfelter’s) genetic diseases- cystic fibrosis, hemophilia, sickle cell anemia . Gene silencing, knockout genes.
LO: To demonstrate diseases caused by mutations in humans and micro-organisms.
LA: Assessment of mutations by analysis, practical observations and essays.
UNIT – VI: EXTRA CHROMOSOMAL INHERITANCE
Introduction to Extra Chromosomal Inheritance, Examples of Extra Chromosomal Inheritance, Petite Phenotypes in Yeast, Uniparental inheritance in Algae.
LO: To demonstrate extra chromosomal inheritance.
LA: Assessment by experimental demonstration.
TEXT BOOKS
- E.J. Gardner, M.J. Simmons & DP Shustad. Principles of Genetics, 2001
REFERENCES
- Goodenough U. Hold Genetics, International2010
- Griffith Genetics 9th edition W. H. Freeman and Company 2007
- Strickberger Genetics 8th edition TBS 2008
- Essentials of Genetics (In genomics prospective), Hartwell, 2003
- Robert H. Tamarin Principles of Genetics-, 7th edition Tata McGraw Hill 2001
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