JNTUK B.Tech Cancer Biology gives you detail information of Cancer Biology R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT I: FUNDAMENTALS OF CANCER BIOLOGY
Regulation of Cell cycle, mutations that cause changes in signal molecules, effects on receptor, signal switches.
LO: To familiarize about regulation of cell cycle and other physical effects.
LA: Assessment by analyzing the regulations of cell cycle and other effects.
UNIT II: TUMOR SUPPRESSION
Tumor suppressor genes, modulation of cell cycle in cancer. Different forms of cancers, Diet and cancer.
LO: To understand the tumor suppressor genes and different forms of cancer.
LA: Assessment by ability to identify the tumor suppressor genes and differentiate between forms of cancers.
UNIT III: PRINCIPLES OF CARCINOGENESIS
Chemical Carcinogenesis, Natural History of Carcinogenesis, Targets of Chemical Carcinogenesis, Metabolism of Carcinogenes. Principles of Physical Carcinogenesis, X -Ray radiation – mechanism of radiation Carcinogenesis.
LO: To understand the principles of carcinogenesis.
LA: Assessment by testing the carcinogenic effects of these molecules on genes.
UNIT IV: MOLECULAR CELL BIOLOGY OF CANCER
Oncogenes, Identification of Oncogenes, Retroviruses and Oncogenes, detection of Oncogenes, Growth Factor and Growth Factor receptors that are Oncogenic.
LO: To demonstrate the oncogenes and its detection and environmental effects on oncogenes.
LA: Assessment by analyzing and evaluating the effects of factors on oncogenes.
UNIT V: PRINCIPLES OF CANCER METASTASIS
Clinical significances of invasion, heterogeneity of metastatic phenotype, Metastatic cascade, Basement Membrane disruption, Three-step theory of Invasion, Proteinases and tumor cell invasion.
LO: To understand the principles of cancer metastasis.
LA: Assessment by analyzing and demonstrating the mechanism of metastasis.
UNIT VI: DETECTION AND THERAPEUTIC MOLECULES
Detection of Cancers, Prediction of aggressiveness of Cancer, Advances in Cancer detection. Different forms of therapy, Chemotherapy, radiation Therapy, and Immunotherapy: advantages and limitations.
LO: To know about the new molecules for cancer therapy and detection
LA: Assessment by practical applications of various therapeutic methods
TEXT BOOKS
- Margarett Knowles, An Introduction to Cellular and Molecular Biology of Cancer, 4th edition, Oxford Medical publications, 2005.
- Weinberg, Cancer biology, 2nd edition, Garland publications, 2013.
REFERENCE
- Dunmock N.J and Primrose.S.B., Introduction to modern Virology, 3rd edition, Blackwell publications, 1987.
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