JNTUK B.Tech Bioprocess Engineering gives you detail information of Bioprocess Engineering R13 syllabus It will be help full to understand you complete curriculum of the year.
UNIT I: INTRODUCTION TO BIOPROCESSES
An overview of traditional and modern applications of biotechnology industry, outline of an integrated bioprocess and the various (upstream and downstream) unit operations involved in bioprocesses, generalized process flow sheets.
LO: To study the traditional and modern applications of various upstream and downstream unit operations.
LA: Assessment by demonstration of various samples by these bioprocess.
UNIT II: FERMENTATION PROCESSES
General requirements of fermentation processes, Basic design and construction of fermenter and ancillaries, Main parameter stobe monitored and controlled in fermentation processes; An overview of aerobic and anaerobic fermentation processes and their application in the biotechnology industry, solid- substrate, slurry fermentation and its applications, whole cell immobilization, behavior of microbes in different reactors (airlift, fluidized, batch, continuous fed batch condition).
LO: To demonstrate the various principles and parameters for designing fermentation.
LA: Assessment by designing customized fermenter based on requirement.
UNIT III: MEDIA DESIGN
Medium requirements for fermentation processes, carbon, nitrogen, minerals, vitamins and other complex nutrients, oxygen requirements, medium formulation for optimal growth and product formation, examples of simple and complex media, design and usage of various commercial media for industrial fermentations.
LO: To study the different requirement of media and its design.
LA: Assessment by practical and objective ability.
UNIT IV: METABOLIC STOICHIOMETRY
Stoichiometry of Cell growth and product formation, elemental balances, degrees of reduction of substrate and biomass, available electron balances, yield coefficients of biomass and product formation, maintenance coefficients.
LO: To study the Stoichiometry balancing of different metabolic reactions.
LA: Assessment by calculation of different types of cell growth.
UNIT V: ENERGETICS
Energetic analysis of microbial growth and product formation, oxygen consumption and heat evolution in aerobic cultures, thermodynamic efficiency of growth.
LO: To study the various microbial growth requirements in different cultures.
LA: Assessment by analysis of different types of energetic required for microbial growth.
UNIT VI: KINETICS OF MICROBIAL GROWTH AND PRODUCT FORMATION
Phases of cell growth in batch cultures, Simple unstructured kinetic models for microbial growth, Monod model, Growth of filamentous organisms. Growth associated (primary) and non- growth associated (secondary) product formation Kinetics. Leudeking- Piret models, substrate and product inhibition on cell growth and product formation. Introduction to Structured Models for growth and product formation. Enzyme processes: Production of enzymes in submerged and solid-state processes, extraction and purification of enzymes, methods of characterization, specific activity and activity definitions.
LO: To study the kinetics of microbial growth and product formation.
LA: Assessment by analyzing and calculating various kinetic parameters of growth for different types of microbes.
All relevant units will have basic numerical problems.
TEXTBOOKS
- D. G. Rao, Introduction to Biochemical Engineering, McGraw-Hill, 2005.
- M. L. Shuler and F. Kargi Bioprocess engineering, 2nd edition Prentice Hall of India 2002.
- P. M. Doran, Biochemical process principles,2nd edition Academic Press,2012..
REFERENCES
- Harvey W. Blanch, DouglasS. Clark Biochemical Engineering, Marcecel, Dekker, 2007.
- Bailey Olli’s, Biochemical Engineering fundamentals, edition, McGraw-Hill, 1986.
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