{"id":8320,"date":"2018-08-12T19:06:37","date_gmt":"2018-08-12T19:06:37","guid":{"rendered":"http:\/\/www.inspirenignite.com\/jntuh\/?p=8320"},"modified":"2021-11-05T03:54:11","modified_gmt":"2021-11-05T03:54:11","slug":"jntuh-m-pharm-2017-2018-r17-detailed-syllabus-modern-bio-analytical-techniques","status":"publish","type":"post","link":"https:\/\/www.inspirenignite.com\/jntuh\/jntuh-m-pharm-2017-2018-r17-detailed-syllabus-modern-bio-analytical-techniques\/","title":{"rendered":"JNTUH M.Pharm 2017-2018 (R17) Detailed Syllabus Modern Bio analytical Techniques"},"content":{"rendered":"

Modern Bio analytical Techniques Detailed Syllabus for Pharmaceutical Analysis & Quality Assurance \/ Quality Assurance M.Pharm first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.<\/p>\n

The detailed syllabus for Modern Bio analytical Techniques M.Pharm 2017-2018 (R17) first year second sem is as follows.<\/p>\n

M.Pharm. I Year II Sem.<\/p>\n

Course Objectives:<\/strong> This subject is designed to provide detailed knowledge about the importance of analysis of drugs in biological matrices.<\/p>\n

Course Outcomes:<\/strong> Upon completion of the course, the student shall be able to understand<\/p>\n

    \n
  1. Extraction of drugs from biological samples<\/li>\n
  2. Separation of drugs from biological samples using different techniques<\/li>\n
  3. Guidelines for BA\/BE studies<\/li>\n<\/ol>\n

    UNIT I : Extraction of drugs and metabolites from biological matrices:<\/strong> General need, principle and procedure involved in the Bioanalytical methods such as Protein precipitation, Liquid -Liquid extraction and Solid phase extraction and other novel sample preparation approach.<\/p>\n

    UNIT II : Biopharmaceutical Consideration:<\/strong> Introduction, Biopharmaceutical Factors Affecting Drug Bioavailability, In Vitro: Dissolution and Drug Release Testing, Alternative Methods of Dissolution Testing Transport models, Biopharmaceutics Classification System. Solubility: Experimental Methods. Permeability: In-vitro, in-situ and In-vivo methods.<\/p>\n

    UNIT III : Bioanalysis and bioanalytical method validation:<\/strong><\/p>\n

      \n
    1. Types of body fluids, requirement of analysis, matrix effects, non-biological analytical samples.<\/li>\n
    2. Bioanalytical method validation: USFDA and EMEA guidelines. Acceptance criteria in comparison to non-biological samples.<\/li>\n<\/ol>\n

      UNIT IV : Pre-Formulation:\u00a0<\/strong>A consideration of following characteristics of medicinal agents in their dosage form:<\/p>\n

        \n
      1. Physical characteristicsParticle :\u00a0<\/strong>size, polymorphism, crystal form, solubility, Interfacial tension, Salt formation, Wetting of solids, flow characteristics, compressibility, and Partition coefficient.<\/li>\n
      2. Chemical CharacteristicsDegradation:\u00a0<\/strong>Hydrolytic, oxidative, reductive and photolytic, Drug – Excipient Compatibility studies.<\/li>\n<\/ol>\n

        UNIT V<\/strong><\/p>\n

          \n
        1. Automation and computer-aided analysis, LIMS: The concept of auto samplers and high throughput analysis, computer controlled instrumentation and networked laboratory. Peculiarities of laboratory information management systems (LIMS).<\/li>\n
        2. Drug Product Performance, In Vivo: Purpose of Bioavailability Studies, Bioavailability and Bioequivalence Studies, Clinical Significance of Bioequivalence Studies.<\/li>\n<\/ol>\n

          REFERENCES:<\/strong><\/p>\n

            \n
          1. Analysis of drugs in Biological fluids – Joseph Chamberlain, 2nd Edition. CRC Press, New York. 1995.<\/li>\n
          2. Principles of Instrumental Analysis – Doglas A Skoog, F. James Holler, Timothy A. Nieman, 5th edition, Eastern press, Bangalore, 1998.<\/li>\n
          3. Pharmaceutical Analysis – Higuchi, Brochmman and Hassen, 2nd Edition, Wiley \u2013 Interscience Publications, 1961.<\/li>\n
          4. Pharmaceutical Analysis- Modern methods \u2013 Part B – J W Munson, Volume 11, Marcel Dekker Series<\/li>\n
          5. Practical HPLC method Development \u2013 Snyder, Kirkland, Glaich, 2nd Edition, John Wiley & Sons, New Jersey. USA.<\/li>\n
          6. Chromatographic Analysis of Pharmaceuticals \u2013 John A Adamovics, 2nd Edition, Marcel Dekker, Newyork, USA. 1997.<\/li>\n
          7. Chromatographic methods in clinical chemistry & Toxicology \u2013 Roger L Bertholf, Ruth E Winecker, John Wiley & Sons, New Jercy, USA. 2007.<\/li>\n
          8. Good Laboratory Practice Regulations, 2nd Edition, Sandy Weinberg Vol.69, Marcel Dekker Series, 1995.<\/li>\n
          9. Good laboratory Practice Regulations \u2013 Allen F. Hirsch, Volume 38,Marcel Dekker Series, 1989.<\/li>\n
          10. ICH, USFDA & CDSCO Guidelines, Palmer<\/li>\n<\/ol>\n

            For all other M.Pharm 1st Year 2nd Sem syllabus go to\u00a0JNTUH\u00a0M.Pharm Pharmaceutical Analysis & Quality Assurance \/ Quality Assurance 1st Year 2nd Sem Course Structure for (R17) Batch.<\/a><\/em><\/p>\n

            All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.<\/p>\n

            Do share with friends and in case of questions please feel free drop a comment<\/p>\n","protected":false},"excerpt":{"rendered":"

            Modern Bio analytical Techniques Detailed Syllabus for Pharmaceutical Analysis & Quality Assurance \/ Quality Assurance M.Pharm first year second sem is covered here. This gives the details about credits, number […]<\/p>\n","protected":false},"author":2259,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[154,62],"tags":[],"class_list":["post-8320","post","type-post","status-publish","format-standard","hentry","category-m-pharm","category-syllabus"],"_links":{"self":[{"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/posts\/8320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/users\/2259"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/comments?post=8320"}],"version-history":[{"count":3,"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/posts\/8320\/revisions"}],"predecessor-version":[{"id":13697,"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/posts\/8320\/revisions\/13697"}],"wp:attachment":[{"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/media?parent=8320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/categories?post=8320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/jntuh\/wp-json\/wp\/v2\/tags?post=8320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}