Nutraceuticals Detailed Syllabus for Pharmaceutics / Pharmaceutical Technology M.Pharm first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Nutraceuticals Delivery Systems M.Pharm 2017-2018 (R17) first year second sem is as follows.
M.Pharm. I Year II Sem.
Course Objectives: The students will expose to characteristic features of various phytochemicals as neutraceuticals in various diseased conditions and also know the role of antioxidant in free radical induced disease conditions and will expose to various food laws and regulations
Course Outcome: Helps the student to understand the importance of Neutraceuticals in various common problems with the concept of free radicals.
UNIT I
- Definitions of Functional foods, Nutraceuticals and Dietary supplements. Classification of Nutraceuticals, Health problems and diseases that can be prevented or cured by Nutraceuticals i.e. weight control, diabetes, cancer etc.
- Source, Name of marker compounds and their chemical nature, Medicinal uses and health benefits of following used as nutraceuticals/functional foods: Spirulina, Soyabean, Ginseng, Garlic, Broccoli, Gingko, Flaxseeds
UNIT II : Phytochemicals as neutraceuticals: Occurrence and characteristic features(chemical nature medicinal
benefits) of following
- Carotenoids- α and β-Carotene, Lycopene, Xanthophylls, lutein
- Sulfides: Diallylsulfides, Allyltrisulfide.
- Polyphenolics: Reservetrol
- Flavonoids- Rutin , Naringin, Quercitin, Anthocyanidins, catechins, Flavones
- Prebiotates / Probiotics.: Fructo oligosaccharides, Lacto bacillum
- Phytoestrogens : Isoflavones, daidzein, Geebustin, lignans
- Tocopherols
UNIT III
- Introduction to free radicals: Free radicals, reactive oxygen species, production of free radicals in cells, damaging reactions of free radicals on lipids, proteins, Carbohydrates, nucleic acids.
- Measurement of free radicals: Lipid peroxidation products, lipid hydroperoxide, malondialdehyde.
UNIT IV
- Free radicals in Diabetes mellitus, Inflammation, Ischemic reperfusion injury, Cancer, Atherosclerosis, Free radicals in brain metabolism and pathology, kidney damage, muscle damage. Free radicals involvement in other disorders. Free radicals theory of ageing.
- Antioxidants: Endogenous antioxidants – enzymatic and nonenzymatic antioxidant defence, Superoxide dismutase, catalase, Glutathione peroxidase, Glutathione Vitamin C, Vitamin E, α- Lipoic acid, melatonin Synthetic antioxidants: Butylatedhydroxy Toluene, Butylatedhydroxy Anisole.
UNIT V
- Food Laws and Regulations; FDA, FPO, MPO, AGMARK. HACCP and GMPs on Food Safety. Adulteration of foods.
- Regulations and Claims – Current Products: Label Claims, Nutrient Content Claims, Health Claims, Dietary Supplements Claims
REFERENCES:
- Dietetics by Sri Lakshmi
- Role of dietary fibres and neutraceuticals in preventing diseases by K. T Agusti and P. Faizal: BS Publication.
- Advanced Nutritional Therapies by Cooper. K. A., (1996).
- The Food Pharmacy by Jean Carper, Simon & Schuster, UK Ltd., (1988).
- Prescription for Nutritional Healing by James F. Balch and Phyllis A. Balch 2nd Edn. Avery Publishing Group, NY (1997).
- G. Gibson and C. Williams Editors 2000 Functional foods Woodhead Publ. Co. London.
- Goldberg, I. Functional Foods. 1994. Chapman and Hall, New York.
- Labuza, T. P. 2000 Functional Foods and Dietary Supplements: Safety, Good Manufacturing Practice (GMPs) and Shelf Life Testing in Essentials of Functional Foods M. K. Sachmidl and T. P. Labuza eds. Aspen Press.
- Handbook of Nutraceuticals and Functional Foods, Third Edition (Modern Nutrition)
- Shils, ME, Olson, JA, Shike, M. 1994 Modern Nutrition in Health and Disease. Eighth edition. Lea and Febiger
For all other M.Pharm 1st Year 2nd Sem syllabus go to JNTUH M.Pharm Pharmaceutics / Pharmaceutical Technology 1st Year 2nd Sem Course Structure for (R17) Batch.
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