Screening Methods in Pharmacology Detailed Syllabus for Quality Assurance and Pharma Regulatory Affairs M.Pharm first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Screening Methods in Pharmacology M.Pharm 2016-2017 (R16) first year second sem is as follows.
B.Tech. I Year II Sem.
Course Objectives:- The students is going to study about various techniques for screening of drugs for various pharmacological activities and guide lines for handling animals and human and animal ethics for screening of drugs.
Course Outcome: – The expected outcomes are student will know how to handle animals and know about various techniques for screening drugs for different pharmacological activities and guidelines and regulations for screening new drug molecules on animals and human volunteers.
UNIT I: Care Handling and breeding techniques of laboratory animals, CPCSEA guidelines, alternatives to animal studies, Good laboratory Practices.
UNIT II : Bioassays: Basic principles of Biological standardization, Merits and demerits, methods used in the bio-assay of Rabbis Vaccine and Oxytocin. Test for pyrogens.
UNIT III : Toxicity tests: OECD guidelines, determination of LD50, acute, subacute and chronic toxicity studies.
UNIT IV: Screening: Definition, types of screening methods. Pharmacological activity of new substances with emphasis on the evaluation of analgesic, antipyretic and anti-inflammatory activity.
UNIT V: Screening for the Pharmacological activity of epilepsy, cardiac, psychopharmacological, anti diabetic and anticancer.
TEXT BOOKS
- Screening methods in Pharmacology, Vol.-1&2 by Robert .A. Turner and Peter Hebborn.
- Pharmacological Screening Methods & Toxicology by Srinivasa Rao A,Pharmamed press publishers.
- Handbook of experimental pharmacology by S.K. Kulkarni, Vallabh Prakashan, Delhi.
REFERENCE BOOKS
- ICH of technical requirements for registration of pharmaceuticals for human use, ICH harmonized Tripartite guidelines – Guidelines for good clinical practice, E6, May 1996.
- Good clinical practice – Guidelines for Clinical trails on pharmaceutical products in India, Central drug standard control organization, New Delhi, Minister of Health- 2001
For all other B.Tech 1st Year 2nd Sem syllabus go to JNTUH B.Tech B. Pharm 1st Year 2nd Sem Quality Assurance and Pharma Regulatory Affairs Course Structure for (R17) Batch.
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