Pharmaceutical Microbiology Detailed Syllabus for B.Tech third year first sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Pharmaceutical Microbiology B.Tech 2016-2017 (R16) third year first sem is as follows.
B.Tech. III Year I Sem. L/T/P/C
Course Code:PS501 4/1/0/4
Course Objectives: Microbiology is always considered to be an essential component of Pharmacy
curriculum because of its relevance to pharmaceutical sciences and more specifically to pharmaceutical industry.
This course deals with the various aspects of microorganism their classification morphology, laboratory cultivation, identification, maintenance and control of microorganism, sterility testing and biosafety measures. The course also covers bacterial genetics, drug resistance and microbiological assays and microbial limit tests.
Course Outcomes: Upon completion of the subject student shall be able to –
- know the anatomy, identification & cultivation of microorganisms
- Perform sterilization of various pharmaceutical products, equipment, culture media etc.
- Perform sterility testing of pharmaceutical products.
- Perform microbiological assay of antibiotics, Vitamins and amino acids
- Do microbiological analysis of air, water and milk
UNIT I
a. Introduction to Microbiology: Origin, scope and discovery of spontanesous generation theory, contributions of Antony Van Leewenhoek, Louis Pasteur, Robert Koch and Joseph Lister.
b. Diversity of Microorganisms: Prokaryotes versus eukaryotes – three domains of life (bacteria, archea and eurkaryotics). A detailed study of bacteria, yeasts, molds and viruses including their classification. Characterization and identification of microorganisms.
UNIT II
Nutrition and Growth of Microbes: Nutritional requirements, Types of nutrient media and growth
conditions and Nutritional types based on energy source. Isolation, cultivation (aerobic & anaerobic) and preservation of microorganisms, physiology of growth, bacterial growth curve, influence of various factors (including environmental factors) on microbial growth, Enumeration of bacteria. Exponential growth and generation time. Bacterial growth in batch and continous culture (chemostat and turbidostat) synchronous growth.
UNIT III
a. Control of Microorganisms: General concepts, Inhibition of growth and killing, sterilization and disinfection, antisepis and sanitation, mode of action applications & limitations of physical agents (moist and dry heat, radiation and filtration) and chemical agents. Various types of disinfectants, factors affecting sterilization and disinfection, evaluation of antimicrobial activity.
b. Official methods of sterility testing of pharmaceuticals and biosafety measures.
TEXT BOOKS
- Pelzar and Reid, Text Book of Microbiology
- Anantha Narayan and Jayram Panikar, Text Book of Microbiology, Orient Longman, Delhi, Hyderabad.
- Indian Pharmacopoeia, 1996
REFERENCES
- Tortora / Funke / Care / Microbiology an introduction.
- Stephen. P, Denyer, N.A. Hodger- Hugo & Russel’s Pharmaceutical Microbiology .
For all other B.Tech 3rd Year 1st Sem syllabus go to JNTUH B.Tech B. Pharm 3rd Year 1st Sem Course Structure for (R16) Batch.
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