JNTUH B.Pharm 2nd year (R13206) Pharmaceutical Organic Chemistry-II Lab gives you detail (R13206) Pharmaceutical Organic Chemistry-II Lab Engineering R13 year subject. It will be help full you to understand you complete curriculum of the year.
I. Synthesis of some simple heterocyclic compounds.
- 3, 5-Dimethylpyrazole from Acetylacetone.
- 3, 5-Dimethylisoxazole from Acetylacetone.
- 4, 5-Diphenylimidazole from Benzil.
- Benzoxazole from o-Aminophenol.
- 2, 5-Dioxopiperazine from Glycine.
- Oxazolone from Benzoylglycine.
II. Molecular rearrangements and named reactions
- Benzimidazole from o-phenylenediamine (Phillip’s Reaction).
- O-hydroxyacetophenone from phenyl acetate (Fries migration)
- Benzanilide from benzophenone oxime (Beckmann’s rearrangement)
- Preparation of 2-phenylindole from Phenylhydrazine by Fischer’s method.
III. Systematic analysis of organic binary mixtures (Minimum 4 numbers)
REFERENCES
- Indian Pharmacopoeia– 2010.
- A.I. Vogel’s – Practical Organic Chemistry
- Mann and Sounders, Pratical organic chemistry
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