{"id":61385,"date":"2023-09-06T17:18:05","date_gmt":"2023-09-06T17:18:05","guid":{"rendered":"https:\/\/www.inspirenignite.com\/anna-university\/cpy331-computer-aided-drug-design-syllabus-for-biotech-2021-regulation-professional-elective-vi\/"},"modified":"2023-09-06T17:18:05","modified_gmt":"2023-09-06T17:18:05","slug":"cpy331-computer-aided-drug-design-syllabus-for-biotech-2021-regulation-professional-elective-vi","status":"publish","type":"post","link":"https:\/\/www.inspirenignite.com\/anna-university\/cpy331-computer-aided-drug-design-syllabus-for-biotech-2021-regulation-professional-elective-vi\/","title":{"rendered":"CPY331: Computer Aided Drug Design syllabus for BioTech 2021 regulation (Professional Elective-VI)"},"content":{"rendered":"

Computer Aided Drug Design detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna Universities<\/a> official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below. <\/p>\n

For Biotechnology 7th Sem scheme and its subjects, do visit BioTech 7th Sem 2021 regulation scheme<\/a>. For Professional Elective-VI scheme and its subjects refer to BioTech Professional Elective-VI syllabus scheme<\/a>. The detailed syllabus of computer aided drug design is as follows. <\/p>\n

Course Objectives:<\/h4>\n

Download the iStudy App for all syllabus and other updates.<\/a>
\"Get<\/a><\/h4>\n

Unit I<\/h4>\n

ELECTRONIC STRUCTURE METHODS\t8<\/strong>
\nQuantum chemical methods semi-empirical and ab initio methods. Conformational analysis, energy minimization, predicting the mechanism of organic reactions using electronic structure methods.\n<\/p>\n

Unit II<\/h4>\n

MOLECULAR MODELING\t9<\/strong>
\nBioactive vs. global minimum conformations. Automated methods of conformational search. Advantages and limitations of available software. Molecular graphics. Computer methodologies behind molecular modeling including artificial intelligence methods.\n<\/p>\n

Unit III<\/h4>\n

Download the iStudy App for all syllabus and other updates.<\/a>
\"Get<\/a><\/h4>\n

Unit IV<\/h4>\n

QSAR: ELECTRONIC EFFECTS\t9<\/strong>
\nHammett equation, lipophilicity effects. Hansch equation, steric effects. Taft equation. Experimental and theoretical approaches for the determination of physicochemical parameters, parameter interdependence: Regression analysis, Descriptor calculation. The importance of biological data in the correct form; 2D QSAR; 3D-QSAR examples of CoMFA and CoMSIA.\n<\/p>\n

Unit V<\/h4>\n

MOLECULAR DOCKING\t10<\/strong>
\nRigid docking, flexible docking, manual docking. Advantages and disadvantages of Flex-X, Flex-S,Autodock and Dock softwares, with successful examples. Dynamics of drugs, biomolecules, drug receptor complexes, Monte Carlo simulations and Molecular dynamics in performing conformational search and docking.\n<\/p>\n

Course Outcomes:<\/h4>\n

The students will be able to<\/p>\n

    \n
  1. Gain knowledge about fundamental concepts, challenges, and rich opportunities in developing and applying algorithms for structural bioinformatics and healthcare.<\/li>\n
  2. Interpret and practice the fundamental concepts of Molecular Modeling and Computer aided Drug Design.<\/li>\n
  3. Develop practical skills in computational approaches to analyse, predict, and engineer biomolecules and biomolecular systems.<\/li>\n
  4. Find a chemical compound that can fit to a specific cavity on a protein target both geometrically and chemically.<\/li>\n
  5. Present the appropriate tools for such a modelling, ranging from electronic Structure methods, Molecular modelling, Structure Activity Relationships in drug design, QSAR, Molecular docking and Molecular dynamics<\/li>\n
  6. Apply the fundamental tools in techniques like docking, modelling, electronic structure methods which leads to new drug target design.<\/li>\n<\/ol>\n

    Text Books:<\/h4>\n

    Download the iStudy App for all syllabus and other updates.<\/a>
    \"Get<\/a><\/h4>\n

    Reference Books:<\/h4>\n
      \n
    1. Donald J. Abraham, Burger\u2019s Medicinal Chemistry and Drug Discovery, Vol V, 6th Edition, John Wiley and Sons, Inc., 2003.<\/li>\n
    2. John B. Taylor and David J. Triggle, Comprehensive Medicinal Chemistry II, Vol IV, Elsevier Science, 2006.<\/li>\n
    3. Graham L. Patrick, An Introduction to Medicinal Chemistry, 5th Edition, Oxford University Press, UK, 2013.<\/li>\n
    4. David. C. Young, Computational Drug Design – A Guide for Computational and Medicinal Chemists, John Wiley and Sons Ltd, Hoboken, United States, 2009.<\/li>\n
    5. Alan Hinchliffe, Molecular Modelling for Beginners, 2nd Edition, Wiley, United University of California, 2008.<\/li>\n<\/li>\n<\/ol>\n

      For detailed syllabus of all the other subjects of Biotechnology 7th Sem, visit BioTech 7th Sem subject syllabuses for 2021 regulation<\/a>. <\/p>\n

      For all Biotechnology results, visit Anna University BioTech all semester results<\/a> direct link. <\/p>\n","protected":false},"excerpt":{"rendered":"

      Computer Aided Drug Design detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BioTech students. For course […]<\/p>\n","protected":false},"author":2297,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[81],"tags":[],"class_list":["post-61385","post","type-post","status-publish","format-standard","hentry","category-biotech"],"_links":{"self":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts\/61385","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/users\/2297"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/comments?post=61385"}],"version-history":[{"count":0,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts\/61385\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/media?parent=61385"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/categories?post=61385"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/tags?post=61385"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}