{"id":59476,"date":"2023-09-06T07:55:14","date_gmt":"2023-09-06T07:55:14","guid":{"rendered":"https:\/\/www.inspirenignite.com\/anna-university\/bi3007-metabolic-engineering-syllabus-for-bbe-2021-regulation-professional-elective-ii\/"},"modified":"2023-09-06T07:55:14","modified_gmt":"2023-09-06T07:55:14","slug":"bi3007-metabolic-engineering-syllabus-for-bbe-2021-regulation-professional-elective-ii","status":"publish","type":"post","link":"https:\/\/www.inspirenignite.com\/anna-university\/bi3007-metabolic-engineering-syllabus-for-bbe-2021-regulation-professional-elective-ii\/","title":{"rendered":"BI3007: Metabolic Engineering syllabus for BBE 2021 regulation (Professional Elective-II)"},"content":{"rendered":"

Metabolic Engineering detailed syllabus for Biotechnology & Biochemical Engineering (BBE) for 2021 regulation curriculum has been taken from the Anna Universities<\/a> official website and presented for the BBE students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below. <\/p>\n

For Biotechnology & Biochemical Engineering 5th Sem scheme and its subjects, do visit BBE 5th Sem 2021 regulation scheme<\/a>. For Professional Elective-II scheme and its subjects refer to BBE Professional Elective-II syllabus scheme<\/a>. The detailed syllabus of metabolic engineering is as follows. <\/p>\n

Course Objectives:<\/h4>\n

Download the iStudy App for all syllabus and other updates.<\/a>
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Unit I<\/h4>\n

CELL METABOLIC ENGINEERING, METABOLIC PATHWAYS\t9<\/strong>
\nImprovement of cellular properties, altering transport of nutrients including carbon and nitrogen; Methods for metabolic characterization: Genome, Transcriptome, Proteome. Feedback control systems, alteration of feedback regulation for enhanced production of primary metabolites: glutamic acid, Mutants which do not produce feedback inhibitors or repressors- Auxotrophslysine, purine nucleotides; trophophase- idiophase relationship; secondary metabolites- Antibiotics, Mycotoxins\n<\/p>\n

Unit II<\/h4>\n

MANIPULATION OF METABOLIC PATHWAYS\t9<\/strong>
\nPathway manipulation strategies for overproduction of various metabolites, examples of ethanol overproduction, overproduction of intermediates in main glycolytic pathway and TCA cycle like pyruvate, succinate; Tools for multiple genomic modifications examples- TALENS CRISPR-Cas systems as well as traditional systems of gene knock ins and knock outs and promoter engineering.\n<\/p>\n

Unit III<\/h4>\n

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Unit IV<\/h4>\n

BASICS OF SYNTHETIC BIOLOGY\t9<\/strong>
\nSynthetic biology – definitions and concepts. History and evolution of synthetic biology and engineering perspectives. Natural vs Engineering systems. Tools of synthetic biology -Key enabling technologies in synthetic biology. BioBricks – Definition of a BioBrick\n<\/p>\n

Unit V<\/h4>\n

APPLICATIONS OF METABOLIC ENGINEERING AND SYNTHETIC BIOLOGY 9
\nProduct over production examples: amino acids, By-product minimization of acetate in recombinant E. coli, Extension of substrate utilization range for organisms such as S. cerevisae for ethanol production; Application of synthetic biology with a case study.\n<\/p>\n

Course Outcomes:<\/h4>\n
    \n
  1. Comprehend modern biology with engineering principles<\/li>\n
  2. Recall the basic principles and regulation of metabolic pathways<\/li>\n
  3. Construct suitable metabolic flux models using available metabolic engineering tools<\/li>\n
  4. Identify the appropriate host and\/or metabolic pathways to produce a desired product<\/li>\n
  5. Compare the potential metabolic engineering strategies using quantitative metabolic modelling<\/li>\n
  6. Apply the concept of synthetic biology in interdisciplinary research<\/li>\n<\/ol>\n

    Text Books:<\/h4>\n

    Download the iStudy App for all syllabus and other updates.<\/a>
    \"Get<\/a><\/h4>\n

    Reference Books:<\/h4>\n
      \n
    1. Freemont, P.S and Kitney, R.I. (2012). Synthetic Biology – a Primer. World Scientific Publishing Co pvt Ltd<\/li>\n
    2. Peter F. Stanbury, Stephen J. Hall & A. Whitaker, \u201cPrinciples of Fermentation Technology\u201d, Butterworth – Heinemann An Imprint of Elsevier India Pvt. Ltd., 3rd edition, 2016<\/li>\n
    3. Crueger W. and Crueger A., \u201cA Text Book of Industrial Microbiology\u201d, Panima Publishing Corporation, 2005<\/li>\n
    4. Cheng Q. \u201cMicrobial Metabolic Engineering: Methods and Protocols\u201d, Humana Press, First Edition (2011).<\/li>\n
    5. Lehninger, A. L, Nelson D. L and Cox, M. M, \u201cPrinciples of Biochemistry\u201d, Freeman Publishers, New York, Seventh edition, 2017<\/li>\n<\/li>\n<\/ol>\n

      For detailed syllabus of all the other subjects of Biotechnology & Biochemical Engineering 5th Sem, visit BBE 5th Sem subject syllabuses for 2021 regulation<\/a>. <\/p>\n

      For all Biotechnology & Biochemical Engineering results, visit Anna University BBE all semester results<\/a> direct link. <\/p>\n","protected":false},"excerpt":{"rendered":"

      Metabolic Engineering detailed syllabus for Biotechnology & Biochemical Engineering (BBE) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BBE students. For […]<\/p>\n","protected":false},"author":2297,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[154],"tags":[],"class_list":["post-59476","post","type-post","status-publish","format-standard","hentry","category-bbe"],"_links":{"self":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts\/59476","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/users\/2297"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/comments?post=59476"}],"version-history":[{"count":0,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts\/59476\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/media?parent=59476"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/categories?post=59476"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/tags?post=59476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}