{"id":21136,"date":"2019-12-10T07:22:21","date_gmt":"2019-12-10T07:22:21","guid":{"rendered":"https:\/\/www.inspirenignite.com\/anna-university\/computer-aided-drug-design-pharma-7th-sem-syllabus-for-b-tech-2017-regulation-anna-univ-professional-elective-v\/"},"modified":"2019-12-10T07:22:21","modified_gmt":"2019-12-10T07:22:21","slug":"computer-aided-drug-design-pharma-7th-sem-syllabus-for-b-tech-2017-regulation-anna-univ-professional-elective-v","status":"publish","type":"post","link":"https:\/\/www.inspirenignite.com\/anna-university\/computer-aided-drug-design-pharma-7th-sem-syllabus-for-b-tech-2017-regulation-anna-univ-professional-elective-v\/","title":{"rendered":"Computer Aided Drug Design Pharma 7th Sem Syllabus for B.Tech 2017 Regulation Anna Univ (Professional Elective V)"},"content":{"rendered":"<p>Computer Aided Drug Design Pharma 7th Sem Syllabus for B.Tech 2017 Regulation Anna Univ (Professional Elective V) detail syllabus for Pharmacy (Pharma), 2017 regulation is collected from the <a href=\"https:\/\/www.annauniv.edu\/\" target=\"_blank\" rel=\"noopener\">Anna Univ<\/a> official website and presented for students of Anna University. The details of the course are: course code (PY8016), Category (PE), Contact Periods\/week (3), Teaching hours\/week (3), Practical Hours\/week (0). The total course credits are given in combined syllabus.<\/p>\n<p>For all other pharma 7th sem syllabus for b.tech 2017 regulation anna univ you can visit <a href=\"..\/pharma-7th-sem-syllabus-for-b-tech-2017-regulation-anna-univ\">Pharma 7th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects<\/a>. For all other Professional Elective V subjects do refer to <a href=\"..\/professional-elective-v-pharma-7th-sem-syllabus-for-b-tech-2017-regulation-anna-univ\">Professional Elective V<\/a>. The detail syllabus for computer aided drug design is as follows.<\/p>\n<p><h4>Course Objective:<\/h4>\n<p>The objective of this course is<\/p>\n<ul>\n<li>to find a chemical compound that can fit to a specific cavity on a protein target both geometrically and chemically.<\/li>\n<li>to know the informatics approaches to the prediction of chemical properties of new drugs<\/li>\n<li>to present the appropriate tools for such a modelling, ranging from electronic Structure methods, Molecular modelling, Structure Activity Relationships in drug design, QSAR, Molecular docking and Molecular dynamics<\/li>\n<\/ul>\n<p><h4>Unit I<\/h4>\n<p>For complete syllabus and results, class timetable and more pls <a href=\"https:\/\/play.google.com\/store\/apps\/details?id=ini.istudy\" target=\"_blank\" rel=\"noopener\">download iStudy<\/a>. Its a light weight, easy to use, no images, no pdfs platform to make students life easier.<\/p>\n<p><h4>Unit II<\/h4>\n<p><strong>Molecular Modeling<\/strong><br \/>\nBioactive vs. global minimum conformations. Automated methods of conformational search. Advantages and limitations of available software. Molecular graphics. Computer methodologies behind molecular modeling including artificial intelligence methods.\n<\/p>\n<p><h4>Unit III<\/h4>\n<p><strong>Structure Activity Relationships in Drug Design<\/strong><br \/>\nQualitative versus quantitative approaches advantages and disadvantages. Random screening, Non-random screening, rational approaches to lead discovery. Homologation, chain branching, ring-chain transformations. Insights into molecular recognition phenomenon. Structure based drug design, ligand based drug design.\n<\/p>\n<p><h4>Unit IV<\/h4>\n<p>For complete syllabus and results, class timetable and more pls <a href=\"https:\/\/play.google.com\/store\/apps\/details?id=ini.istudy\" target=\"_blank\" rel=\"noopener\">download iStudy<\/a>. Its a light weight, easy to use, no images, no pdfs platform to make students life easier.<\/p>\n<p><h4>Unit V<\/h4>\n<p><strong>Molecular Docking<\/strong><br \/>\nRigid docking, flexible docking, manual docking. Advantages and disadvantages of Flex-X, Flex-S, Autodock and Dock softwares, with successful examples. Dynamics of drugs, biomolecules, drugreceptor complexes, Monte Carlo simulations and Molecular dynamics in performing conformational search and docking.\n<\/p>\n<p><h4>Course Outcome:<\/h4>\n<p>The student able<\/p>\n<ul>\n<li>To gain knowledge about fundamental concepts, challenges, and rich opportunities in developing and applying algorithms for structural bioinformatics and healthcare.<\/li>\n<li>To interpret and practice the fundamental concepts of Molecular Modeling and Computer-aided Drug Design.<\/li>\n<li>To develop practical skills in computational approaches to analyze, predict, and engineer biomolecules and biomolecular systems.<\/li>\n<\/ul>\n<p><h4>Text Books:<\/h4>\n<ol>\n<li>Andrew R. Leach, Molecular Modelling Principle and Application, 2nd Edition, Prentice Hall, England,2001.<\/li>\n<li>Richard B. Silverman, Mark W. Holladay, Organic Chemistry of Drug Design and Drug Action, 3rd Edition, Academic Press, USA, 2014.<\/li>\n<li>Paul S. Charifson, Practical Applications of computer aided drug design, 1st Edition, Marcel Dekker, New York, 1997.<\/li>\n<li>J. M. Goodman, Chemical Applications of Molecular Modelling, The Royal Society of Chemistry, Cambridge, 1998.<\/li>\n<\/ol>\n<p><h4>References:<\/h4>\n<ol>\n<li>Donald J. Abraham, Burgers Medicinal Chemistry and Drug Discovery, Vol V, 6th Edition, John Wiley and Sons, Inc., 2003.<\/li>\n<li>John B. Taylor and David J. Triggle, Comprehensive Medicinal Chemistry II, Vol IV, Elsevier Science, 2006.<\/li>\n<li>Graham L. Patrick, An Introduction to Medicinal Chemistry, 5th Edition, Oxford University Press, UK, 2013.<\/li>\n<li>David. C. Young, Computational Drug Design &#8211; A Guide for Computational and Medicinal Chemists, John Wiley and Sons Ltd, Hoboken, United States, 2009.<\/li>\n<li>Alan Hinchliffe, Molecular Modelling for Beginners, 2nd Edition, Wiley, United University of California, 2008.<\/li>\n<\/li>\n<\/ol>\n<p>For detail syllabus of all other subjects of B.Tech Pharma, 2017 regulation do visit <a href=\"..\/category\/pharma+7th-sem\">Pharma 7th Sem syllabus for 2017 Regulation<\/a>.<\/p>\n<p>Dont forget to <a href=\"https:\/\/play.google.com\/store\/apps\/details?id=ini.istudy\" target=\"_blank\" rel=\"noopener\">download iStudy<\/a> for latest syllabus and results, class timetable and more.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Computer Aided Drug Design Pharma 7th Sem Syllabus for B.Tech 2017 Regulation Anna Univ (Professional Elective V) detail syllabus for Pharmacy (Pharma), 2017 regulation is collected from the Anna Univ [&hellip;]<\/p>\n","protected":false},"author":2297,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[50,90],"tags":[],"class_list":["post-21136","post","type-post","status-publish","format-standard","hentry","category-7th-sem","category-pharma"],"_links":{"self":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts\/21136","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/users\/2297"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/comments?post=21136"}],"version-history":[{"count":0,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/posts\/21136\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/media?parent=21136"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/categories?post=21136"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.inspirenignite.com\/anna-university\/wp-json\/wp\/v2\/tags?post=21136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}